ERK1/2 mitogen‐activated protein kinase dimerization is essential for the regulation of cell motility

ERK1/2 mitogen‐activated protein kinase dimerization is essential for the regulation of cell motility

ERK1/2 mitogen‐activated protein kinases (ERK) are key regulators of basic cellular processes, including proliferation, survival, and migration. Upon phosphorylation, ERK becomes activated and a portion of it dimerizes. The importance of ERK activation in specific cellular events is generally well d...

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Main Authors: Dalia de laFuente‐Vivas, Vincenzo Cappitelli, Rocío García‐Gómez, Sara Valero‐Díaz, Camilla Amato, Javier Rodriguéz, Santiago Duro‐Sánchez, Alexander vonKriegsheim, Michael Grusch, José Lozano, Joaquín Arribas, Berta Casar, Piero Crespo
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Molecular Oncology
Subjects:
cell motility
ERK
KSR
MAP kinases
scaffold proteins
Online Access:https://doi.org/10.1002/1878-0261.13732
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