Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos
The low efficiency observed in cloning by nuclear transfer is related to an aberrant gene expression following errors in epigenetic reprogramming. Recent studies have focused on further understanding of the modifications that take place in the chromatin of embryos during the preimplantation period,...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Veterinary Medicine International |
| Online Access: | http://dx.doi.org/10.4061/2011/694817 |
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| _version_ | 1832556558497611776 |
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| author | Fabio Morato Monteiro Clara Slade Oliveira Letícia Zoccolaro Oliveira Naiara Zoccal Saraiva Maria Eugênia Zerlotti Mercadante Flavia Lombardi Lopes Daniel Robert Arnold Joaquim Mansano Garcia |
| author_facet | Fabio Morato Monteiro Clara Slade Oliveira Letícia Zoccolaro Oliveira Naiara Zoccal Saraiva Maria Eugênia Zerlotti Mercadante Flavia Lombardi Lopes Daniel Robert Arnold Joaquim Mansano Garcia |
| author_sort | Fabio Morato Monteiro |
| collection | DOAJ |
| description | The low efficiency observed in cloning by nuclear transfer is related to an aberrant gene expression following errors in epigenetic reprogramming. Recent studies have focused on further understanding of the modifications that take place in the chromatin of embryos during the preimplantation period, through the use of chromatin modifying agents. The goal of these studies is to identify the factors involved in nuclear reprogramming and to adjust in vitro manipulations in order to better mimic in vivo conditions. Therefore, proper knowledge of epigenetic reprogramming is necessary to prevent possible epigenetic errors and to improve efficiency and the use of in vitro fertilization and cloning technologies in cattle and other species. |
| format | Article |
| id | doaj-art-88874620162d4823a2f4a3c83fbb2352 |
| institution | Kabale University |
| issn | 2042-0048 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Veterinary Medicine International |
| spelling | doaj-art-88874620162d4823a2f4a3c83fbb23522025-02-03T05:45:01ZengWileyVeterinary Medicine International2042-00482011-01-01201110.4061/2011/694817694817Chromatin Modifying Agents in the In Vitro Production of Bovine EmbryosFabio Morato Monteiro0Clara Slade Oliveira1Letícia Zoccolaro Oliveira2Naiara Zoccal Saraiva3Maria Eugênia Zerlotti Mercadante4Flavia Lombardi Lopes5Daniel Robert Arnold6Joaquim Mansano Garcia7Departamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilDepartamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilDepartamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilDepartamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilInstituto de Zootecnia, Estação Experimental de Zootecnia de Sertãozinho, Caixa Postal 63, 14.160-970-Sertãozinho, SP, BrazilDepartamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilDepartamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilDepartamento de Reprodução Animal, FCAV-UNESP, 14884-000-Jaboticabal, SP, BrazilThe low efficiency observed in cloning by nuclear transfer is related to an aberrant gene expression following errors in epigenetic reprogramming. Recent studies have focused on further understanding of the modifications that take place in the chromatin of embryos during the preimplantation period, through the use of chromatin modifying agents. The goal of these studies is to identify the factors involved in nuclear reprogramming and to adjust in vitro manipulations in order to better mimic in vivo conditions. Therefore, proper knowledge of epigenetic reprogramming is necessary to prevent possible epigenetic errors and to improve efficiency and the use of in vitro fertilization and cloning technologies in cattle and other species.http://dx.doi.org/10.4061/2011/694817 |
| spellingShingle | Fabio Morato Monteiro Clara Slade Oliveira Letícia Zoccolaro Oliveira Naiara Zoccal Saraiva Maria Eugênia Zerlotti Mercadante Flavia Lombardi Lopes Daniel Robert Arnold Joaquim Mansano Garcia Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos Veterinary Medicine International |
| title | Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos |
| title_full | Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos |
| title_fullStr | Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos |
| title_full_unstemmed | Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos |
| title_short | Chromatin Modifying Agents in the In Vitro Production of Bovine Embryos |
| title_sort | chromatin modifying agents in the in vitro production of bovine embryos |
| url | http://dx.doi.org/10.4061/2011/694817 |
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