Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow
Background/Objectives: Antimicrobial resistance is a global threat to safe health care, and a reduction in antibiotic consumption seems to be an appropriate preventive measure. In Germany, the reporting of hospital antibiotics consumption to an independent institution is only voluntary. Although a h...
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MDPI AG
2025-01-01
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| Series: | Antibiotics |
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| author | Bianca Leistner Dominic Rauschning Ralf Matthias Hagen Franziska Srečec Nico Tom Mutters Ruth Weppler Christina Mutschnik Manuel Döhla |
| author_facet | Bianca Leistner Dominic Rauschning Ralf Matthias Hagen Franziska Srečec Nico Tom Mutters Ruth Weppler Christina Mutschnik Manuel Döhla |
| author_sort | Bianca Leistner |
| collection | DOAJ |
| description | Background/Objectives: Antimicrobial resistance is a global threat to safe health care, and a reduction in antibiotic consumption seems to be an appropriate preventive measure. In Germany, the reporting of hospital antibiotics consumption to an independent institution is only voluntary. Although a high level of willingness to improve can be assumed in the case of participation, the median consumptions of reporting hospitals change only slightly. This study examines the question of whether the logistical consumption figures adequately reflect real consumption, and if not, how to optimize the use of logistical data for clinical decisions. Methods: Four selected wards were analyzed during six months. A retrospective analysis of patient case files was performed to receive “prescribed daily doses” (PDDs). These were compared to “defined daily doses” (DDDs) from logistical data. Additional inventories were performed to calculated stored antibiotics. Antibiotics goods flows were presented via waterfall diagrams to identify logistic patterns that could explain PDD/DDD quotients. Antimicrobial stewardship (AMS) quality indicators were analyzed to give advice for optimized clinical AMS measures. Results: The total PDD/DDD quotient was 0.69. Four logistical patterns were identified. Optimized prophylaxis, AMS consultations and reevaluation of therapy seem to be the most useful measures to reduce PDDs. Conclusions: If AMS programs rely solely on DDDs, measures cannot be optimal. A complete consideration of antibiotic goods flows supports clinical decisions, but is very costly in terms of data collection. The consideration of logistical data can help to identify areas of focus for AMS programs. Therefore, specialists of antibiotics logistics should complement clinical AMS teams. |
| format | Article |
| id | doaj-art-8879019d799048bda6048cd1b608d471 |
| institution | Kabale University |
| issn | 2079-6382 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj-art-8879019d799048bda6048cd1b608d4712025-01-24T13:18:41ZengMDPI AGAntibiotics2079-63822025-01-011414310.3390/antibiotics14010043Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods FlowBianca Leistner0Dominic Rauschning1Ralf Matthias Hagen2Franziska Srečec3Nico Tom Mutters4Ruth Weppler5Christina Mutschnik6Manuel Döhla7Institute for Hygiene and Public Health, Medical Faculty, University of Bonn, Haus 33, 53113 Bonn, GermanyClinic Ia of Internal Medicine, Bundeswehr Central Hospital Koblenz, 56070 Koblenz, GermanyDepartment XXI of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56070 Koblenz, GermanyDepartment XXI of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56070 Koblenz, GermanyInstitute for Hygiene and Public Health, Medical Faculty, University of Bonn, Haus 33, 53113 Bonn, GermanyDepartment XXI of Microbiology and Hospital Hygiene, Bundeswehr Central Hospital Koblenz, 56070 Koblenz, GermanyDepartment XXIV of Hospital Pharmacy, Bundeswehr Central Hospital Koblenz, 56070 Koblenz, GermanyInstitute for Hygiene and Public Health, Medical Faculty, University of Bonn, Haus 33, 53113 Bonn, GermanyBackground/Objectives: Antimicrobial resistance is a global threat to safe health care, and a reduction in antibiotic consumption seems to be an appropriate preventive measure. In Germany, the reporting of hospital antibiotics consumption to an independent institution is only voluntary. Although a high level of willingness to improve can be assumed in the case of participation, the median consumptions of reporting hospitals change only slightly. This study examines the question of whether the logistical consumption figures adequately reflect real consumption, and if not, how to optimize the use of logistical data for clinical decisions. Methods: Four selected wards were analyzed during six months. A retrospective analysis of patient case files was performed to receive “prescribed daily doses” (PDDs). These were compared to “defined daily doses” (DDDs) from logistical data. Additional inventories were performed to calculated stored antibiotics. Antibiotics goods flows were presented via waterfall diagrams to identify logistic patterns that could explain PDD/DDD quotients. Antimicrobial stewardship (AMS) quality indicators were analyzed to give advice for optimized clinical AMS measures. Results: The total PDD/DDD quotient was 0.69. Four logistical patterns were identified. Optimized prophylaxis, AMS consultations and reevaluation of therapy seem to be the most useful measures to reduce PDDs. Conclusions: If AMS programs rely solely on DDDs, measures cannot be optimal. A complete consideration of antibiotic goods flows supports clinical decisions, but is very costly in terms of data collection. The consideration of logistical data can help to identify areas of focus for AMS programs. Therefore, specialists of antibiotics logistics should complement clinical AMS teams.https://www.mdpi.com/2079-6382/14/1/43antimicrobial stewardshipquality indicatordefined daily doseprescribed daily doseantibiotic resistanceantibiotic consumption |
| spellingShingle | Bianca Leistner Dominic Rauschning Ralf Matthias Hagen Franziska Srečec Nico Tom Mutters Ruth Weppler Christina Mutschnik Manuel Döhla Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow Antibiotics antimicrobial stewardship quality indicator defined daily dose prescribed daily dose antibiotic resistance antibiotic consumption |
| title | Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow |
| title_full | Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow |
| title_fullStr | Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow |
| title_full_unstemmed | Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow |
| title_short | Logistic Stewardship: Supporting Antimicrobial Stewardship Programs Based on Antibiotics Goods Flow |
| title_sort | logistic stewardship supporting antimicrobial stewardship programs based on antibiotics goods flow |
| topic | antimicrobial stewardship quality indicator defined daily dose prescribed daily dose antibiotic resistance antibiotic consumption |
| url | https://www.mdpi.com/2079-6382/14/1/43 |
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