The Evolution of Prognostic Factors in Multiple Myeloma

Multiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last decade, the dis...

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Main Authors: Amr Hanbali, Mona Hassanein, Walid Rasheed, Mahmoud Aljurf, Fahad Alsharif
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Advances in Hematology
Online Access:http://dx.doi.org/10.1155/2017/4812637
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author Amr Hanbali
Mona Hassanein
Walid Rasheed
Mahmoud Aljurf
Fahad Alsharif
author_facet Amr Hanbali
Mona Hassanein
Walid Rasheed
Mahmoud Aljurf
Fahad Alsharif
author_sort Amr Hanbali
collection DOAJ
description Multiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last decade, the disease remains incurable. All efforts are currently focused on understanding the prognostic markers of the disease hoping to incorporate the new therapeutic modalities to convert the disease into curable one. We present this comprehensive review to summarize the current standard prognostic markers used in MM along with novel techniques that are still in development and highlight their implications in current clinical practice.
format Article
id doaj-art-886ba6bf5e8b4f82b7f63ff803545bc2
institution Kabale University
issn 1687-9104
1687-9112
language English
publishDate 2017-01-01
publisher Wiley
record_format Article
series Advances in Hematology
spelling doaj-art-886ba6bf5e8b4f82b7f63ff803545bc22025-02-03T05:49:21ZengWileyAdvances in Hematology1687-91041687-91122017-01-01201710.1155/2017/48126374812637The Evolution of Prognostic Factors in Multiple MyelomaAmr Hanbali0Mona Hassanein1Walid Rasheed2Mahmoud Aljurf3Fahad Alsharif4King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaMultiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last decade, the disease remains incurable. All efforts are currently focused on understanding the prognostic markers of the disease hoping to incorporate the new therapeutic modalities to convert the disease into curable one. We present this comprehensive review to summarize the current standard prognostic markers used in MM along with novel techniques that are still in development and highlight their implications in current clinical practice.http://dx.doi.org/10.1155/2017/4812637
spellingShingle Amr Hanbali
Mona Hassanein
Walid Rasheed
Mahmoud Aljurf
Fahad Alsharif
The Evolution of Prognostic Factors in Multiple Myeloma
Advances in Hematology
title The Evolution of Prognostic Factors in Multiple Myeloma
title_full The Evolution of Prognostic Factors in Multiple Myeloma
title_fullStr The Evolution of Prognostic Factors in Multiple Myeloma
title_full_unstemmed The Evolution of Prognostic Factors in Multiple Myeloma
title_short The Evolution of Prognostic Factors in Multiple Myeloma
title_sort evolution of prognostic factors in multiple myeloma
url http://dx.doi.org/10.1155/2017/4812637
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