The Evolution of Prognostic Factors in Multiple Myeloma
Multiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last decade, the dis...
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Format: | Article |
Language: | English |
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Wiley
2017-01-01
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Series: | Advances in Hematology |
Online Access: | http://dx.doi.org/10.1155/2017/4812637 |
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author | Amr Hanbali Mona Hassanein Walid Rasheed Mahmoud Aljurf Fahad Alsharif |
author_facet | Amr Hanbali Mona Hassanein Walid Rasheed Mahmoud Aljurf Fahad Alsharif |
author_sort | Amr Hanbali |
collection | DOAJ |
description | Multiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last decade, the disease remains incurable. All efforts are currently focused on understanding the prognostic markers of the disease hoping to incorporate the new therapeutic modalities to convert the disease into curable one. We present this comprehensive review to summarize the current standard prognostic markers used in MM along with novel techniques that are still in development and highlight their implications in current clinical practice. |
format | Article |
id | doaj-art-886ba6bf5e8b4f82b7f63ff803545bc2 |
institution | Kabale University |
issn | 1687-9104 1687-9112 |
language | English |
publishDate | 2017-01-01 |
publisher | Wiley |
record_format | Article |
series | Advances in Hematology |
spelling | doaj-art-886ba6bf5e8b4f82b7f63ff803545bc22025-02-03T05:49:21ZengWileyAdvances in Hematology1687-91041687-91122017-01-01201710.1155/2017/48126374812637The Evolution of Prognostic Factors in Multiple MyelomaAmr Hanbali0Mona Hassanein1Walid Rasheed2Mahmoud Aljurf3Fahad Alsharif4King Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi ArabiaMultiple myeloma (MM) is a heterogeneous hematologic malignancy involving the proliferation of plasma cells derived by different genetic events contributing to the development, progression, and prognosis of this disease. Despite improvement in treatment strategies of MM over the last decade, the disease remains incurable. All efforts are currently focused on understanding the prognostic markers of the disease hoping to incorporate the new therapeutic modalities to convert the disease into curable one. We present this comprehensive review to summarize the current standard prognostic markers used in MM along with novel techniques that are still in development and highlight their implications in current clinical practice.http://dx.doi.org/10.1155/2017/4812637 |
spellingShingle | Amr Hanbali Mona Hassanein Walid Rasheed Mahmoud Aljurf Fahad Alsharif The Evolution of Prognostic Factors in Multiple Myeloma Advances in Hematology |
title | The Evolution of Prognostic Factors in Multiple Myeloma |
title_full | The Evolution of Prognostic Factors in Multiple Myeloma |
title_fullStr | The Evolution of Prognostic Factors in Multiple Myeloma |
title_full_unstemmed | The Evolution of Prognostic Factors in Multiple Myeloma |
title_short | The Evolution of Prognostic Factors in Multiple Myeloma |
title_sort | evolution of prognostic factors in multiple myeloma |
url | http://dx.doi.org/10.1155/2017/4812637 |
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