Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections
Mycoplasmoses of cattle and small ruminants, pigs and poultry are widely spread and the infection process is frequently associated with other diseases. Mycoplasma spp. cause inflammatory respiratory diseases, diseases of joints and meninges, keratoconjunctivitis, mastitis and endometritis, abortio...
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Da Vinci Media
2022-06-01
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| Series: | Ветеринария сегодня |
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| Online Access: | https://veterinary.arriah.ru/jour/article/view/646 |
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| author | V. A. Agoltsov L. P. Padilo O. P. Biryukova M. M. Ligidova |
| author_facet | V. A. Agoltsov L. P. Padilo O. P. Biryukova M. M. Ligidova |
| author_sort | V. A. Agoltsov |
| collection | DOAJ |
| description | Mycoplasmoses of cattle and small ruminants, pigs and poultry are widely spread and the infection process is frequently associated with other diseases. Mycoplasma spp. cause inflammatory respiratory diseases, diseases of joints and meninges, keratoconjunctivitis, mastitis and endometritis, abortion and stillbirths. Etiotropic therapy of mycoplasmal infections consists in prescribing antibiotics: enrofloxacin, difloxacin, oxytetracycline, chlortetracycline, doxycycline, tylosin, tilmicosin, tylvalosin, tiamulin, florfenicol, lincomycin, spectinomycin, tulathromycin. The results of studies described in different publications show high sensitivity of Mycoplasma synoviae and Mycoplasma gallisepticum to tetracyclines, tiamulin and tylvalosin. Isolates with increased resistance to tilmicosin are also resistant to tylosin and lincomycin. Treatment of respiratory infections in lambs, the main causative agents of which are Mannheimia haemolytica and Mycoplasma, has been successful with the use of fluoroquinolones, tilmicosin, tulathromycin, chlortetracycline, enrofloxacin, doxycycline, and oxytetracycline. Isolates of Mycoplasma bovis are largely sensitive to oxytetracycline, florfenicol and tulathromycin. Enrofloxacin has a less pronounced therapeutic effect. Tilmicosin and oxytetracycline are effective in the treatment of respiratory diseases of young cattle, associated with Mycoplasma spp. Tulathromycin and tilmicosin have a significant therapeutic effect in the treatment of pneumonia in weaned piglets experimentally infected with Mycoplasma hyopneumoniae. Multiple (course) use of enrofloxacin significantly increases the therapeutic effect. Tilmicosin is effective in the control of other bacterial infections of pigs (pasteurellosis, streptococcosis, hemophilic polyserositis, infectious atrophic rhinitis).The general prophylaxis of mycoplasmal infections is to comply with veterinary and sanitary standards and to implement quarantine measures in the infection outbreak. |
| format | Article |
| id | doaj-art-8868d9be504f4a819149fa26af299b51 |
| institution | Kabale University |
| issn | 2304-196X 2658-6959 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Da Vinci Media |
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| series | Ветеринария сегодня |
| spelling | doaj-art-8868d9be504f4a819149fa26af299b512025-02-06T09:52:09ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592022-06-0111216917510.29326/2304-196X-2022-11-2-169-175568Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infectionsV. A. Agoltsov0L. P. Padilo1O. P. Biryukova2M. M. Ligidova3Saratov State Agrarian University named after N.I. VavilovSaratov State Agrarian University named after N.I. VavilovSaratov State Agrarian University named after N.I. VavilovSaratov State Agrarian University named after N.I. VavilovMycoplasmoses of cattle and small ruminants, pigs and poultry are widely spread and the infection process is frequently associated with other diseases. Mycoplasma spp. cause inflammatory respiratory diseases, diseases of joints and meninges, keratoconjunctivitis, mastitis and endometritis, abortion and stillbirths. Etiotropic therapy of mycoplasmal infections consists in prescribing antibiotics: enrofloxacin, difloxacin, oxytetracycline, chlortetracycline, doxycycline, tylosin, tilmicosin, tylvalosin, tiamulin, florfenicol, lincomycin, spectinomycin, tulathromycin. The results of studies described in different publications show high sensitivity of Mycoplasma synoviae and Mycoplasma gallisepticum to tetracyclines, tiamulin and tylvalosin. Isolates with increased resistance to tilmicosin are also resistant to tylosin and lincomycin. Treatment of respiratory infections in lambs, the main causative agents of which are Mannheimia haemolytica and Mycoplasma, has been successful with the use of fluoroquinolones, tilmicosin, tulathromycin, chlortetracycline, enrofloxacin, doxycycline, and oxytetracycline. Isolates of Mycoplasma bovis are largely sensitive to oxytetracycline, florfenicol and tulathromycin. Enrofloxacin has a less pronounced therapeutic effect. Tilmicosin and oxytetracycline are effective in the treatment of respiratory diseases of young cattle, associated with Mycoplasma spp. Tulathromycin and tilmicosin have a significant therapeutic effect in the treatment of pneumonia in weaned piglets experimentally infected with Mycoplasma hyopneumoniae. Multiple (course) use of enrofloxacin significantly increases the therapeutic effect. Tilmicosin is effective in the control of other bacterial infections of pigs (pasteurellosis, streptococcosis, hemophilic polyserositis, infectious atrophic rhinitis).The general prophylaxis of mycoplasmal infections is to comply with veterinary and sanitary standards and to implement quarantine measures in the infection outbreak.https://veterinary.arriah.ru/jour/article/view/646reviewmycoplasmosistreatmentpoultrysmall and large cattlepigsenrofloxacindifloxacinoxytetracyclinechlortetracyclinedoxycyclinetylosintilmicosintylvalosintiamulinflorfenicollincomycinspectinomycintulathromycin |
| spellingShingle | V. A. Agoltsov L. P. Padilo O. P. Biryukova M. M. Ligidova Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections Ветеринария сегодня review mycoplasmosis treatment poultry small and large cattle pigs enrofloxacin difloxacin oxytetracycline chlortetracycline doxycycline tylosin tilmicosin tylvalosin tiamulin florfenicol lincomycin spectinomycin tulathromycin |
| title | Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections |
| title_full | Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections |
| title_fullStr | Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections |
| title_full_unstemmed | Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections |
| title_short | Effectiveness and safety of therapeutics used for treatment of experimental or spontaneous <i>Mycoplasma</i> infections |
| title_sort | effectiveness and safety of therapeutics used for treatment of experimental or spontaneous i mycoplasma i infections |
| topic | review mycoplasmosis treatment poultry small and large cattle pigs enrofloxacin difloxacin oxytetracycline chlortetracycline doxycycline tylosin tilmicosin tylvalosin tiamulin florfenicol lincomycin spectinomycin tulathromycin |
| url | https://veterinary.arriah.ru/jour/article/view/646 |
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