Avidity of pertussis toxin antibodies following vaccination with genetically versus chemically detoxified pertussis toxin-containing vaccines during pregnancy

Avidity of pertussis toxin antibodies following vaccination with genetically versus chemically detoxified pertussis toxin-containing vaccines during pregnancy

BackgroundBoth the quantity and quality of circulating anti-pertussis toxin antibodies are important for protection against severe pertussis. We compared the avidity of PT-IgG antibodies in pregnant women and their infants following vaccination during pregnancy with pertussis vaccines containing gen...

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Bibliographic Details
Main Authors: Bahaa Abu-Raya, Giuseppe Del Giudice, Anita H. J. van den Biggelaar, Yuxiao Tang, Niranjan Bhat, Hong Thai Pham, Wassana Wijagkanalan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
pertussis
avidity
pertussis toxin
genetically inactivated
recombinant vaccine
maternal immunization
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1569151/full
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