Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses

Background: Despite many published studies on ERβ, progress towards understanding its role in breast cancer remains slow. This is largely due to discordant data between mRNA and protein studies as well as failure to take into account the biologically distinct ERβ isoforms and their heterogeneous exp...

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Main Authors: Michele Cummings, James Iremonger, Caroline A. Green, Abeer M. Shaaban, Valerie Speirs
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Cellular Oncology
Online Access:http://dx.doi.org/10.3233/CLO-2009-0495
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author Michele Cummings
James Iremonger
Caroline A. Green
Abeer M. Shaaban
Valerie Speirs
author_facet Michele Cummings
James Iremonger
Caroline A. Green
Abeer M. Shaaban
Valerie Speirs
author_sort Michele Cummings
collection DOAJ
description Background: Despite many published studies on ERβ, progress towards understanding its role in breast cancer remains slow. This is largely due to discordant data between mRNA and protein studies as well as failure to take into account the biologically distinct ERβ isoforms and their heterogeneous expression profile.
format Article
id doaj-art-885bcf80613c472f853acca7ec0a15fa
institution Kabale University
issn 1570-5870
1875-8606
language English
publishDate 2009-01-01
publisher Wiley
record_format Article
series Cellular Oncology
spelling doaj-art-885bcf80613c472f853acca7ec0a15fa2025-02-03T05:59:10ZengWileyCellular Oncology1570-58701875-86062009-01-0131646747310.3233/CLO-2009-0495Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression AnalysesMichele Cummings0James Iremonger1Caroline A. Green2Abeer M. Shaaban3Valerie Speirs4Leeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UKLeeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UKLeeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UKLeeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UKLeeds Institute of Molecular Medicine, St. James's University Hospital, Leeds, UKBackground: Despite many published studies on ERβ, progress towards understanding its role in breast cancer remains slow. This is largely due to discordant data between mRNA and protein studies as well as failure to take into account the biologically distinct ERβ isoforms and their heterogeneous expression profile.http://dx.doi.org/10.3233/CLO-2009-0495
spellingShingle Michele Cummings
James Iremonger
Caroline A. Green
Abeer M. Shaaban
Valerie Speirs
Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses
Cellular Oncology
title Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses
title_full Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses
title_fullStr Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses
title_full_unstemmed Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses
title_short Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses
title_sort gene expression of erβ isoforms in laser microdissected human breast cancers implications for gene expression analyses
url http://dx.doi.org/10.3233/CLO-2009-0495
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AT carolineagreen geneexpressionoferbisoformsinlasermicrodissectedhumanbreastcancersimplicationsforgeneexpressionanalyses
AT abeermshaaban geneexpressionoferbisoformsinlasermicrodissectedhumanbreastcancersimplicationsforgeneexpressionanalyses
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