Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome
We describe the case of a patient who underwent craniectomy for hemorrhage of the left parietal lobe. Three weeks later, orthostatic memory impairment was detected as initial symptom of sinking skin flap syndrome (SSFS). This deficit was examined by neuropsychological testing and associated with a p...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/318917 |
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| author | Luca Sebastianelli Verena Stoll Viviana Versace Sara Martignago Stephan Obletter Marco Lavoriero Kathrin Malfertheiner Gertraud Gisser Leopold Saltuari |
| author_facet | Luca Sebastianelli Verena Stoll Viviana Versace Sara Martignago Stephan Obletter Marco Lavoriero Kathrin Malfertheiner Gertraud Gisser Leopold Saltuari |
| author_sort | Luca Sebastianelli |
| collection | DOAJ |
| description | We describe the case of a patient who underwent craniectomy for hemorrhage of the left parietal lobe. Three weeks later, orthostatic memory impairment was detected as initial symptom of sinking skin flap syndrome (SSFS). This deficit was examined by neuropsychological testing and associated with a posture-dependent increase in the delta/alpha ratio at the F3 electrode, an electroencephalographic (EEG) index related to brain hypoperfusion. This EEG spectral alteration was detected in a brain region that includes the left dorsolateral prefrontal cortex, an area known to be involved in memory processing; therefore we hypothesize that SSFS induced reversible hypoperfusion of this otherwise undamaged cortical region. Neither of these findings was present after cranioplasty. This case suggests that SSFS may induce neuropsychological deficits potentially influencing outcome in the postacute phase and is further evidence supporting the clinical benefits of early cranioplasty. |
| format | Article |
| id | doaj-art-8850875f2eb94622bf2830009259aa8e |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-8850875f2eb94622bf2830009259aa8e2025-02-03T01:11:35ZengWileyCase Reports in Neurological Medicine2090-66682090-66762015-01-01201510.1155/2015/318917318917Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap SyndromeLuca Sebastianelli0Verena Stoll1Viviana Versace2Sara Martignago3Stephan Obletter4Marco Lavoriero5Kathrin Malfertheiner6Gertraud Gisser7Leopold Saltuari8Krankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyKrankenhaus Sterzing, Abteilung Neurorehabilitation, Sterzing, 39049 Bozen, ItalyResearch Unit for Neurorehabilitation of South Tyrol, 39100 Bozen, ItalyWe describe the case of a patient who underwent craniectomy for hemorrhage of the left parietal lobe. Three weeks later, orthostatic memory impairment was detected as initial symptom of sinking skin flap syndrome (SSFS). This deficit was examined by neuropsychological testing and associated with a posture-dependent increase in the delta/alpha ratio at the F3 electrode, an electroencephalographic (EEG) index related to brain hypoperfusion. This EEG spectral alteration was detected in a brain region that includes the left dorsolateral prefrontal cortex, an area known to be involved in memory processing; therefore we hypothesize that SSFS induced reversible hypoperfusion of this otherwise undamaged cortical region. Neither of these findings was present after cranioplasty. This case suggests that SSFS may induce neuropsychological deficits potentially influencing outcome in the postacute phase and is further evidence supporting the clinical benefits of early cranioplasty.http://dx.doi.org/10.1155/2015/318917 |
| spellingShingle | Luca Sebastianelli Verena Stoll Viviana Versace Sara Martignago Stephan Obletter Marco Lavoriero Kathrin Malfertheiner Gertraud Gisser Leopold Saltuari Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome Case Reports in Neurological Medicine |
| title | Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome |
| title_full | Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome |
| title_fullStr | Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome |
| title_full_unstemmed | Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome |
| title_short | Short-Term Memory Impairment and Left Dorsolateral Prefrontal Cortex Dysfunction in the Orthostatic Position: A Single Case Study of Sinking Skin Flap Syndrome |
| title_sort | short term memory impairment and left dorsolateral prefrontal cortex dysfunction in the orthostatic position a single case study of sinking skin flap syndrome |
| url | http://dx.doi.org/10.1155/2015/318917 |
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