Efficacy and safety of immune checkpoint inhibitors in elderly patients with advanced non-small cell lung cancer: a systematic review and meta-analysisResearch in context

Efficacy and safety of immune checkpoint inhibitors in elderly patients with advanced non-small cell lung cancer: a systematic review and meta-analysisResearch in context

Summary: Background: Immune checkpoint inhibitors (ICIs) are the preferred treatments for advanced non-small cell lung cancer (NSCLC) without targetable oncogene alterations. However, evidence in the elderly population (aged ≥ 65 years) remains limited. Methods: We searched PubMed, Embase, Cochrane...

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Bibliographic Details
Main Authors: Jiacheng Yao, Sihan Li, Lu Bai, Jun Chen, Chengbo Ren, Tingting Liu, Jingping Qiu, Jun Dang
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:EClinicalMedicine
Subjects:
Immune checkpoint inhibitors
Overall survival
Non-small cell lung cancer
Elderly
Meta-analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537025000136
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