Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases
The ring system in which a benzene ring is fused to the 4,5-positions of imidazole is designated as benzimidazole. Condensations of 2-substituted benzimidazole derivatives were synthesized by different carboxylic acids using Mannich base and anti-inflammatory activity. The various positions on the b...
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | E-Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2010/601929 |
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| author | B. Anil Reddy |
| author_facet | B. Anil Reddy |
| author_sort | B. Anil Reddy |
| collection | DOAJ |
| description | The ring system in which a benzene ring is fused to the 4,5-positions of imidazole is designated as benzimidazole. Condensations of 2-substituted benzimidazole derivatives were synthesized by different carboxylic acids using Mannich base and anti-inflammatory activity. The various positions on the benzimidazole ring are numbered in the manner indicated with the imino function as number one. The formations of the product were conformed by the analytical and spectral data. |
| format | Article |
| id | doaj-art-880d88d328414166b2abb165bb3cc2ee |
| institution | Kabale University |
| issn | 0973-4945 2090-9810 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | E-Journal of Chemistry |
| spelling | doaj-art-880d88d328414166b2abb165bb3cc2ee2025-02-03T01:21:41ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017122222610.1155/2010/601929Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich BasesB. Anil Reddy0Department of Pharmaceutical Chemistry, Maheshwara College of Pharmacy, Chitkul, Patancheru-500 072, A.P, IndiaThe ring system in which a benzene ring is fused to the 4,5-positions of imidazole is designated as benzimidazole. Condensations of 2-substituted benzimidazole derivatives were synthesized by different carboxylic acids using Mannich base and anti-inflammatory activity. The various positions on the benzimidazole ring are numbered in the manner indicated with the imino function as number one. The formations of the product were conformed by the analytical and spectral data.http://dx.doi.org/10.1155/2010/601929 |
| spellingShingle | B. Anil Reddy Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases E-Journal of Chemistry |
| title | Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases |
| title_full | Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases |
| title_fullStr | Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases |
| title_full_unstemmed | Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases |
| title_short | Synthesis, Characterization and Biological Evaluation of 1, 2-Disubstituted Benzimidazole Derivatives using Mannich Bases |
| title_sort | synthesis characterization and biological evaluation of 1 2 disubstituted benzimidazole derivatives using mannich bases |
| url | http://dx.doi.org/10.1155/2010/601929 |
| work_keys_str_mv | AT banilreddy synthesischaracterizationandbiologicalevaluationof12disubstitutedbenzimidazolederivativesusingmannichbases |