Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis

Hypereosinophilic syndrome (HES) is a rare disorder with unknown global prevalence, barely reported in Hispanic population, and characterized by persistent eosinophilia in association with organ dysfunctions directly attributable to eosinophilic infiltration. Cardiac involvement may be present in 50...

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Main Authors: Mario Enrique Baltazares-Lipp, Juan Ignacio Soto-González, Carlos Manuel Aboitiz-Rivera, Héctor A. Carmona-Ruíz, Benito Sarabia Ortega, Ruben Blachman-Braun
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2016/2359532
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author Mario Enrique Baltazares-Lipp
Juan Ignacio Soto-González
Carlos Manuel Aboitiz-Rivera
Héctor A. Carmona-Ruíz
Benito Sarabia Ortega
Ruben Blachman-Braun
author_facet Mario Enrique Baltazares-Lipp
Juan Ignacio Soto-González
Carlos Manuel Aboitiz-Rivera
Héctor A. Carmona-Ruíz
Benito Sarabia Ortega
Ruben Blachman-Braun
author_sort Mario Enrique Baltazares-Lipp
collection DOAJ
description Hypereosinophilic syndrome (HES) is a rare disorder with unknown global prevalence, barely reported in Hispanic population, and characterized by persistent eosinophilia in association with organ dysfunctions directly attributable to eosinophilic infiltration. Cardiac involvement may be present in 50 to 60% of the patients. This is known as Löffler endocarditis. We present a case of a 36-year-old Hispanic man with signs of heart failure. Laboratory studies showed eosinophilia (23,100/μL). Thoracic computer tomography showed bilateral pleural effusion and a large left ventricular mass. Transthoracic echocardiography showed left ventricle apical obliteration and a restrictive pattern. Pulmonary angiography demonstrated a thrombus in the lingular and middle lobe. Despite treatment, the patient deceased seven days after admission. Autopsy confirmed the diagnosis of Löffler endocarditis.
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institution Kabale University
issn 2090-6404
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language English
publishDate 2016-01-01
publisher Wiley
record_format Article
series Case Reports in Cardiology
spelling doaj-art-87d15b442a2e4d5a93da3a8f2a32b7ca2025-02-03T05:44:28ZengWileyCase Reports in Cardiology2090-64042090-64122016-01-01201610.1155/2016/23595322359532Hypereosinophilic Syndrome: A Case of Fatal Löffler EndocarditisMario Enrique Baltazares-Lipp0Juan Ignacio Soto-González1Carlos Manuel Aboitiz-Rivera2Héctor A. Carmona-Ruíz3Benito Sarabia Ortega4Ruben Blachman-Braun5Departamento de Hemodinamia y Ecocardiografía, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosío Villegas”, 14080 Mexico City, MexicoDepartamento de Hemodinamia y Ecocardiografía, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosío Villegas”, 14080 Mexico City, MexicoDepartamento de Hemodinamia y Ecocardiografía, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosío Villegas”, 14080 Mexico City, MexicoDepartamento de Hemodinamia y Ecocardiografía, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosío Villegas”, 14080 Mexico City, MexicoDepartamento de Hemodinamia y Ecocardiografía, Instituto Nacional de Enfermedades Respiratorias “Ismael Cosío Villegas”, 14080 Mexico City, MexicoFacultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Estado de México, MexicoHypereosinophilic syndrome (HES) is a rare disorder with unknown global prevalence, barely reported in Hispanic population, and characterized by persistent eosinophilia in association with organ dysfunctions directly attributable to eosinophilic infiltration. Cardiac involvement may be present in 50 to 60% of the patients. This is known as Löffler endocarditis. We present a case of a 36-year-old Hispanic man with signs of heart failure. Laboratory studies showed eosinophilia (23,100/μL). Thoracic computer tomography showed bilateral pleural effusion and a large left ventricular mass. Transthoracic echocardiography showed left ventricle apical obliteration and a restrictive pattern. Pulmonary angiography demonstrated a thrombus in the lingular and middle lobe. Despite treatment, the patient deceased seven days after admission. Autopsy confirmed the diagnosis of Löffler endocarditis.http://dx.doi.org/10.1155/2016/2359532
spellingShingle Mario Enrique Baltazares-Lipp
Juan Ignacio Soto-González
Carlos Manuel Aboitiz-Rivera
Héctor A. Carmona-Ruíz
Benito Sarabia Ortega
Ruben Blachman-Braun
Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis
Case Reports in Cardiology
title Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis
title_full Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis
title_fullStr Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis
title_full_unstemmed Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis
title_short Hypereosinophilic Syndrome: A Case of Fatal Löffler Endocarditis
title_sort hypereosinophilic syndrome a case of fatal loffler endocarditis
url http://dx.doi.org/10.1155/2016/2359532
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