Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier

Retinopathy of prematurity (ROP) is a retinal disorder that can cause blindness in premature infants with low birth weight. Early detection and timely treatment are crucial to prevent blindness associated with ROP. It's essential to identify the stage and presence of Plus disease accurately whe...

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Main Authors: Ranjana Agrawal, Sucheta Kulkarni, Madan Deshpande, Anita Gaikwad, Rahee Walambe, Ketan V. Kotecha
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:MethodsX
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Online Access:http://www.sciencedirect.com/science/article/pii/S2215016125000305
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author Ranjana Agrawal
Sucheta Kulkarni
Madan Deshpande
Anita Gaikwad
Rahee Walambe
Ketan V. Kotecha
author_facet Ranjana Agrawal
Sucheta Kulkarni
Madan Deshpande
Anita Gaikwad
Rahee Walambe
Ketan V. Kotecha
author_sort Ranjana Agrawal
collection DOAJ
description Retinopathy of prematurity (ROP) is a retinal disorder that can cause blindness in premature infants with low birth weight. Early detection and timely treatment are crucial to prevent blindness associated with ROP. It's essential to identify the stage and presence of Plus disease accurately when examining retinal images of at-risk infants. We are developing an explainable automated ROP screening system for the HVDROPDB datasets. The fundus images were classified as without stage (Normal)/with Stage (ROP) by segmenting the ridge. Stages 1–3 were classified using machine Learning (ML) models. • This study aims to improve accuracy of Stages 1–3 classification and identify Pre-plus/ Plus disease using MultiCNN_LSTM networks. This is accomplished by using multiple CNNs (Convolutional Neural Networks) to extract features and LSTM (Long Short-Term Memory) classifier to classify images. • Cropped STAGE dataset and HVDROPDB-PLUS dataset are constructed with RetCam and Neo images. • The proposed networks outperform individual CNNs and CNN_LSTM networks in terms of accuracy and F1 score.
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institution Kabale University
issn 2215-0161
language English
publishDate 2025-06-01
publisher Elsevier
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series MethodsX
spelling doaj-art-87cc80371937493295a1dd0d716f068d2025-01-29T05:01:20ZengElsevierMethodsX2215-01612025-06-0114103182Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifierRanjana Agrawal0Sucheta Kulkarni1Madan Deshpande2Anita Gaikwad3Rahee Walambe4Ketan V. Kotecha5Dr. Vishwanath Karad MIT World Peace University, Pune, India; Corresponding author.PBMA's H. V. Desai Eye Hospital, Pune, IndiaPBMA's H. V. Desai Eye Hospital, Pune, IndiaPBMA's H. V. Desai Eye Hospital, Pune, IndiaE&TC dept,Symbiosis Institute of Technology, Associate faculty Symbiosis Centre for Applied Artificial Intelligence (SCAAI), Symbiosis International (Deemed) University, Pune, IndiaSymbiosis Institute of Technology, Symbiosis Centre for Applied Artificial Intelligence (SCAAI), Symbiosis International (Deemed) University, Pune 412 115, Maharashtra, IndiaRetinopathy of prematurity (ROP) is a retinal disorder that can cause blindness in premature infants with low birth weight. Early detection and timely treatment are crucial to prevent blindness associated with ROP. It's essential to identify the stage and presence of Plus disease accurately when examining retinal images of at-risk infants. We are developing an explainable automated ROP screening system for the HVDROPDB datasets. The fundus images were classified as without stage (Normal)/with Stage (ROP) by segmenting the ridge. Stages 1–3 were classified using machine Learning (ML) models. • This study aims to improve accuracy of Stages 1–3 classification and identify Pre-plus/ Plus disease using MultiCNN_LSTM networks. This is accomplished by using multiple CNNs (Convolutional Neural Networks) to extract features and LSTM (Long Short-Term Memory) classifier to classify images. • Cropped STAGE dataset and HVDROPDB-PLUS dataset are constructed with RetCam and Neo images. • The proposed networks outperform individual CNNs and CNN_LSTM networks in terms of accuracy and F1 score.http://www.sciencedirect.com/science/article/pii/S2215016125000305MultiCNN_LSTM classifier for Classification of Early Stages and Pre-plus, plus disease of ROP
spellingShingle Ranjana Agrawal
Sucheta Kulkarni
Madan Deshpande
Anita Gaikwad
Rahee Walambe
Ketan V. Kotecha
Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier
MethodsX
MultiCNN_LSTM classifier for Classification of Early Stages and Pre-plus, plus disease of ROP
title Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier
title_full Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier
title_fullStr Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier
title_full_unstemmed Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier
title_short Classification of Stages 1,2,3 and Preplus, Plus disease of ROP using MultiCNN_LSTM classifier
title_sort classification of stages 1 2 3 and preplus plus disease of rop using multicnn lstm classifier
topic MultiCNN_LSTM classifier for Classification of Early Stages and Pre-plus, plus disease of ROP
url http://www.sciencedirect.com/science/article/pii/S2215016125000305
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