Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens
Purpose. To evaluate the relationship between self-reported vision-related quality of life (VRQL) and visual field (VF) loss in people from glaucoma clinics. Methods. A postal survey using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was administered to people with a range o...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/1621640 |
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| author | Lee Jones Susan R. Bryan David P. Crabb |
| author_facet | Lee Jones Susan R. Bryan David P. Crabb |
| author_sort | Lee Jones |
| collection | DOAJ |
| description | Purpose. To evaluate the relationship between self-reported vision-related quality of life (VRQL) and visual field (VF) loss in people from glaucoma clinics. Methods. A postal survey using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was administered to people with a range of VF loss identified from a UK hospital-based glaucoma service database. Trends were assessed in a composite score from NEI VFQ-25 against better-eye mean deviation (BEMD) using linear regression and a spline-fitting method that can highlight where a monotonic relationship may have different stages. Results. A total of 636 patients (median [interquartile range] BEMD −2.1 [−5.2, −0.4] dB, median age 70 [60, 77] years) were analysed. Analysis of trends in the data revealed an average patient loses approximately 2 units (out of 100) on NEI VFQ-25 for every loss of 1 dB (BEMD) as VF defects first become bilateral, up to BEMD −5 dB. NEI VFQ-25 deterioration then appears to slow before a more rapid phase of change (4–5 units per 1 dB loss) after BEMD worsens beyond −15 dB. Conclusions. Relationship between decline in VRQL and VF worsening in glaucoma is unlikely to be linear; it more likely has different phases, and these should be further explored in longitudinal studies. |
| format | Article |
| id | doaj-art-87c2f50019c542ad81f96df600492574 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-87c2f50019c542ad81f96df6004925742025-02-03T05:48:01ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/16216401621640Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma WorsensLee Jones0Susan R. Bryan1David P. Crabb2Division of Optometry and Visual Science, School of Health Sciences, City, University of London, London, UKDivision of Optometry and Visual Science, School of Health Sciences, City, University of London, London, UKDivision of Optometry and Visual Science, School of Health Sciences, City, University of London, London, UKPurpose. To evaluate the relationship between self-reported vision-related quality of life (VRQL) and visual field (VF) loss in people from glaucoma clinics. Methods. A postal survey using the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was administered to people with a range of VF loss identified from a UK hospital-based glaucoma service database. Trends were assessed in a composite score from NEI VFQ-25 against better-eye mean deviation (BEMD) using linear regression and a spline-fitting method that can highlight where a monotonic relationship may have different stages. Results. A total of 636 patients (median [interquartile range] BEMD −2.1 [−5.2, −0.4] dB, median age 70 [60, 77] years) were analysed. Analysis of trends in the data revealed an average patient loses approximately 2 units (out of 100) on NEI VFQ-25 for every loss of 1 dB (BEMD) as VF defects first become bilateral, up to BEMD −5 dB. NEI VFQ-25 deterioration then appears to slow before a more rapid phase of change (4–5 units per 1 dB loss) after BEMD worsens beyond −15 dB. Conclusions. Relationship between decline in VRQL and VF worsening in glaucoma is unlikely to be linear; it more likely has different phases, and these should be further explored in longitudinal studies.http://dx.doi.org/10.1155/2017/1621640 |
| spellingShingle | Lee Jones Susan R. Bryan David P. Crabb Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens Journal of Ophthalmology |
| title | Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens |
| title_full | Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens |
| title_fullStr | Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens |
| title_full_unstemmed | Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens |
| title_short | Gradually Then Suddenly? Decline in Vision-Related Quality of Life as Glaucoma Worsens |
| title_sort | gradually then suddenly decline in vision related quality of life as glaucoma worsens |
| url | http://dx.doi.org/10.1155/2017/1621640 |
| work_keys_str_mv | AT leejones graduallythensuddenlydeclineinvisionrelatedqualityoflifeasglaucomaworsens AT susanrbryan graduallythensuddenlydeclineinvisionrelatedqualityoflifeasglaucomaworsens AT davidpcrabb graduallythensuddenlydeclineinvisionrelatedqualityoflifeasglaucomaworsens |