An Update on Corneal Biomechanics and Architecture in Diabetes

In the last decade, we have witnessed substantial progress in our understanding of corneal biomechanics and architecture. It is well known that diabetes is a systemic metabolic disease that causes chronic progressive damage in the main organs of the human body, including the eyeball. Although the ma...

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Main Authors: María A. del Buey, Paula Casas, Constanza Caramello, Nuria López, Marisa de la Rica, Ana B. Subirón, Elena Lanchares, Valentín Huerva, Andrzej Grzybowski, Francisco J. Ascaso
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2019/7645352
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author María A. del Buey
Paula Casas
Constanza Caramello
Nuria López
Marisa de la Rica
Ana B. Subirón
Elena Lanchares
Valentín Huerva
Andrzej Grzybowski
Francisco J. Ascaso
author_facet María A. del Buey
Paula Casas
Constanza Caramello
Nuria López
Marisa de la Rica
Ana B. Subirón
Elena Lanchares
Valentín Huerva
Andrzej Grzybowski
Francisco J. Ascaso
author_sort María A. del Buey
collection DOAJ
description In the last decade, we have witnessed substantial progress in our understanding of corneal biomechanics and architecture. It is well known that diabetes is a systemic metabolic disease that causes chronic progressive damage in the main organs of the human body, including the eyeball. Although the main and most widely recognized ocular effect of diabetes is on the retina, the structure of the cornea (the outermost and transparent tissue of the eye) can also be affected by the poor glycemic control characterizing diabetes. The different corneal structures (epithelium, stroma, and endothelium) are affected by specific complications of diabetes. The development of new noninvasive diagnostic technologies has provided a better understanding of corneal tissue modifications. The objective of this review is to describe the advances in the knowledge of the corneal alterations that diabetes can induce.
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institution Kabale University
issn 2090-004X
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publishDate 2019-01-01
publisher Wiley
record_format Article
series Journal of Ophthalmology
spelling doaj-art-87bc659b459c4a5281bc2484d565a9d52025-02-03T06:07:55ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/76453527645352An Update on Corneal Biomechanics and Architecture in DiabetesMaría A. del Buey0Paula Casas1Constanza Caramello2Nuria López3Marisa de la Rica4Ana B. Subirón5Elena Lanchares6Valentín Huerva7Andrzej Grzybowski8Francisco J. Ascaso9Department of Ophthalmology, Hospital Clínico Universitario “Lozano Blesa”, Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario “Lozano Blesa”, Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario “Lozano Blesa”, Zaragoza, SpainDepartment of Ophthalmology, Hospital Clínico Universitario “Lozano Blesa”, Zaragoza, SpainAragón Health Research Institute (IIS Aragon), Zaragoza, SpainAragón Health Research Institute (IIS Aragon), Zaragoza, SpainAragon Institute of Engineering Research (13A), University of Zaragoza, Zaragoza, SpainDepartment of Ophthalmology, Hospital Universitario Arnau de Vilanova, Lleida, SpainDepartment of Ophthalmology, University of Warmia and Mazury, Olsztyn, PolandDepartment of Ophthalmology, Hospital Clínico Universitario “Lozano Blesa”, Zaragoza, SpainIn the last decade, we have witnessed substantial progress in our understanding of corneal biomechanics and architecture. It is well known that diabetes is a systemic metabolic disease that causes chronic progressive damage in the main organs of the human body, including the eyeball. Although the main and most widely recognized ocular effect of diabetes is on the retina, the structure of the cornea (the outermost and transparent tissue of the eye) can also be affected by the poor glycemic control characterizing diabetes. The different corneal structures (epithelium, stroma, and endothelium) are affected by specific complications of diabetes. The development of new noninvasive diagnostic technologies has provided a better understanding of corneal tissue modifications. The objective of this review is to describe the advances in the knowledge of the corneal alterations that diabetes can induce.http://dx.doi.org/10.1155/2019/7645352
spellingShingle María A. del Buey
Paula Casas
Constanza Caramello
Nuria López
Marisa de la Rica
Ana B. Subirón
Elena Lanchares
Valentín Huerva
Andrzej Grzybowski
Francisco J. Ascaso
An Update on Corneal Biomechanics and Architecture in Diabetes
Journal of Ophthalmology
title An Update on Corneal Biomechanics and Architecture in Diabetes
title_full An Update on Corneal Biomechanics and Architecture in Diabetes
title_fullStr An Update on Corneal Biomechanics and Architecture in Diabetes
title_full_unstemmed An Update on Corneal Biomechanics and Architecture in Diabetes
title_short An Update on Corneal Biomechanics and Architecture in Diabetes
title_sort update on corneal biomechanics and architecture in diabetes
url http://dx.doi.org/10.1155/2019/7645352
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