Synthesis of some benzimidazole derivatives endowed with 1,2,3-triazole as potential inhibitors of hepatitis C virus

Synthesis of some benzimidazole derivatives endowed with 1,2,3-triazole as potential inhibitors of hepatitis C virus

New derivatives of 2-thiobenzimidazole incorporating triazole moiety were synthesized, characterized and tested in vitro for antiviral activity against hepatitis C virus (HCV) and hepatitis B virus (HBV). Their cytotoxicity was determined by the reduction in the number of viable cell. All of the syn...

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Bibliographic Details
Main Authors: Youssif Bahaa G. M., Mohamed Yaseen A. M., Salim Mohammed T. A., Inagaki Fuyuhiko, Mukai Chisato, Abdu-Allah Hajjaj H. M.
Format: Article
Language:English
Published: Sciendo 2016-06-01
Series:Acta Pharmaceutica
Subjects:
benzimidazole
triazole
anilide
antiviral
hcv
hbv
Online Access:https://doi.org/10.1515/acph-2016-0014
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