Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases

Introduction. Peritoneal mesothelioma is a rare tumor, presenting difficulties in diagnosis and treatment. Peritoneum is the second most common area of the mesothelioma after pleura, and even synchronous pleural and peritoneal mesotheliomas are observed in 30–45% of all cases. The diagnosis may be d...

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Main Authors: Mustafa Cem Algın, Faik Yaylak, Zülfü Bayhan, Figen Aslan, Nilüfer Araz Bayhan
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2014/748469
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author Mustafa Cem Algın
Faik Yaylak
Zülfü Bayhan
Figen Aslan
Nilüfer Araz Bayhan
author_facet Mustafa Cem Algın
Faik Yaylak
Zülfü Bayhan
Figen Aslan
Nilüfer Araz Bayhan
author_sort Mustafa Cem Algın
collection DOAJ
description Introduction. Peritoneal mesothelioma is a rare tumor, presenting difficulties in diagnosis and treatment. Peritoneum is the second most common area of the mesothelioma after pleura, and even synchronous pleural and peritoneal mesotheliomas are observed in 30–45% of all cases. The diagnosis may be difficult due to lack of specific symptoms and clinical findings. In addition, a delay in the diagnosis is not rare especially in the absence of previous asbestos exposure. Here we report two cases of malignant peritoneal mesotheliomas. The diagnostic and therapeutic approaches for these rare neoplasms are discussed. Case Presentation. The cases were two men (one aged 54 years old and the other 40 years old). Prolonged abdominal pain and swelling were the primary presentation symptoms and findings. The mesotheliomas were developed in the right upper quadrant of abdomen in both of the cases. Both cases were treated with surgical resection. Final diagnosis were possible with histological and immunohistochemical documentation of tumor characteristics, which were consistent with dictating a mesothelial origin. No history of asbestos exposure was reported. Conclusion. Peritoneal mesotheliomas are rare clinical entities. However, patients with prolonged abdominal pain and abdominal masses should be considered to have atypical pathologies such as peritoneal mesotheliomas.
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institution Kabale University
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language English
publishDate 2014-01-01
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record_format Article
series Case Reports in Surgery
spelling doaj-art-87ab62acf46343c6aef9a576c6c8d43c2025-02-03T07:25:34ZengWileyCase Reports in Surgery2090-69002090-69192014-01-01201410.1155/2014/748469748469Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two CasesMustafa Cem Algın0Faik Yaylak1Zülfü Bayhan2Figen Aslan3Nilüfer Araz Bayhan4Department of General Surgery, Faculty of Medicine, Dumlupinar University, 43100 Kutahya, TurkeyDepartment of General Surgery, Faculty of Medicine, Dumlupinar University, 43100 Kutahya, TurkeyDepartment of General Surgery, Faculty of Medicine, Dumlupinar University, 43100 Kutahya, TurkeyDepartment of Pathology, Dumlupinar University-Evliya Celebi Training and Research Hospital, 43059 Kutahya, TurkeyDepartment of Anesthesiology and Reanimation, Dumlupinar University-Evliya Celebi Training and Research Hospital, 43059 Kutahya, TurkeyIntroduction. Peritoneal mesothelioma is a rare tumor, presenting difficulties in diagnosis and treatment. Peritoneum is the second most common area of the mesothelioma after pleura, and even synchronous pleural and peritoneal mesotheliomas are observed in 30–45% of all cases. The diagnosis may be difficult due to lack of specific symptoms and clinical findings. In addition, a delay in the diagnosis is not rare especially in the absence of previous asbestos exposure. Here we report two cases of malignant peritoneal mesotheliomas. The diagnostic and therapeutic approaches for these rare neoplasms are discussed. Case Presentation. The cases were two men (one aged 54 years old and the other 40 years old). Prolonged abdominal pain and swelling were the primary presentation symptoms and findings. The mesotheliomas were developed in the right upper quadrant of abdomen in both of the cases. Both cases were treated with surgical resection. Final diagnosis were possible with histological and immunohistochemical documentation of tumor characteristics, which were consistent with dictating a mesothelial origin. No history of asbestos exposure was reported. Conclusion. Peritoneal mesotheliomas are rare clinical entities. However, patients with prolonged abdominal pain and abdominal masses should be considered to have atypical pathologies such as peritoneal mesotheliomas.http://dx.doi.org/10.1155/2014/748469
spellingShingle Mustafa Cem Algın
Faik Yaylak
Zülfü Bayhan
Figen Aslan
Nilüfer Araz Bayhan
Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases
Case Reports in Surgery
title Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases
title_full Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases
title_fullStr Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases
title_full_unstemmed Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases
title_short Malignant Peritoneal Mesothelioma: Clinicopathological Characteristics of Two Cases
title_sort malignant peritoneal mesothelioma clinicopathological characteristics of two cases
url http://dx.doi.org/10.1155/2014/748469
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AT faikyaylak malignantperitonealmesotheliomaclinicopathologicalcharacteristicsoftwocases
AT zulfubayhan malignantperitonealmesotheliomaclinicopathologicalcharacteristicsoftwocases
AT figenaslan malignantperitonealmesotheliomaclinicopathologicalcharacteristicsoftwocases
AT niluferarazbayhan malignantperitonealmesotheliomaclinicopathologicalcharacteristicsoftwocases