Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques

One of the key roles of an orthopedic surgeon treating metastatic bone disease (MBD) is fracture risk prediction. Current widely used impending fracture risk tools such as Mirels scoring lack specificity. Two newer methods of fracture risk prediction, CT-based structural rigidity analysis (CTRA) and...

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Main Authors: Shannon M. Kaupp, Kenneth A. Mann, Mark A. Miller, Timothy A. Damron
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Advances in Orthopedics
Online Access:http://dx.doi.org/10.1155/2021/5591715
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author Shannon M. Kaupp
Kenneth A. Mann
Mark A. Miller
Timothy A. Damron
author_facet Shannon M. Kaupp
Kenneth A. Mann
Mark A. Miller
Timothy A. Damron
author_sort Shannon M. Kaupp
collection DOAJ
description One of the key roles of an orthopedic surgeon treating metastatic bone disease (MBD) is fracture risk prediction. Current widely used impending fracture risk tools such as Mirels scoring lack specificity. Two newer methods of fracture risk prediction, CT-based structural rigidity analysis (CTRA) and finite element analysis (FEA), have each been shown to be more accurate than Mirels. This case series illustrates comparative Mirels, CTRA, and FEA for 8 femurs in 7 subjects. These cases were selected from a much larger data set to portray examples of true positives, true negatives, false positives, and false negatives as defined by CTRA relative to the fracture outcome. Case illustrations demonstrate comparative Mirels and FEA. This series illustrates the use, efficacy, and limitations of these tools. As all current tools have limitations, further work is needed in refining and developing fracture risk prediction.
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institution Kabale University
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spelling doaj-art-8797a0b772834db7a7645a567ffc75f62025-02-03T07:23:29ZengWileyAdvances in Orthopedics2090-34642090-34722021-01-01202110.1155/2021/55917155591715Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different TechniquesShannon M. Kaupp0Kenneth A. Mann1Mark A. Miller2Timothy A. Damron3SUNY Upstate Medical University, Department of Orthopedic Surgery, 750 East Adams Street, Syracuse, NY 13210, USASUNY Upstate Medical University, Department of Orthopedic Surgery, 750 East Adams Street, Syracuse, NY 13210, USASUNY Upstate Medical University, Department of Orthopedic Surgery, 750 East Adams Street, Syracuse, NY 13210, USASUNY Upstate Medical University, Department of Orthopedic Surgery, 750 East Adams Street, Syracuse, NY 13210, USAOne of the key roles of an orthopedic surgeon treating metastatic bone disease (MBD) is fracture risk prediction. Current widely used impending fracture risk tools such as Mirels scoring lack specificity. Two newer methods of fracture risk prediction, CT-based structural rigidity analysis (CTRA) and finite element analysis (FEA), have each been shown to be more accurate than Mirels. This case series illustrates comparative Mirels, CTRA, and FEA for 8 femurs in 7 subjects. These cases were selected from a much larger data set to portray examples of true positives, true negatives, false positives, and false negatives as defined by CTRA relative to the fracture outcome. Case illustrations demonstrate comparative Mirels and FEA. This series illustrates the use, efficacy, and limitations of these tools. As all current tools have limitations, further work is needed in refining and developing fracture risk prediction.http://dx.doi.org/10.1155/2021/5591715
spellingShingle Shannon M. Kaupp
Kenneth A. Mann
Mark A. Miller
Timothy A. Damron
Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
Advances in Orthopedics
title Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_full Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_fullStr Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_full_unstemmed Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_short Predicting Fracture Risk in Patients with Metastatic Bone Disease of the Femur: A Pictorial Review Using Three Different Techniques
title_sort predicting fracture risk in patients with metastatic bone disease of the femur a pictorial review using three different techniques
url http://dx.doi.org/10.1155/2021/5591715
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