Exposure to 6-PPD Quinone Disrupts Adsorption and Catabolism of Leucine and Causes Mitochondrial Dysfunction in <i>Caenorhabditis elegans</i>

Exposure to 6-PPD Quinone Disrupts Adsorption and Catabolism of Leucine and Causes Mitochondrial Dysfunction in <i>Caenorhabditis elegans</i>

6-PPD quinone (6-PPDQ) is a derivative from 6-PPD, an antioxidant added in tires. Leucine is an important amino acid that needs to be obtained from the diet. In <i>Caenorhabditis elegans</i>, we examined the effect of 6-PPDQ exposure at environmentally relevant concentrations (ERCs) on t...

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Bibliographic Details
Main Authors: Wei Wang, Yunhui Li, Dayong Wang
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Toxics
Subjects:
leucine
adsorption
catabolism
mitochondrial function
pharmacological treatment
nematodes
Online Access:https://www.mdpi.com/2305-6304/13/7/544
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