Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis
The development of artificial organelles is a new, fast-growing field in which a variety of techniques have been employed. This article gives a brief overview of the history of artificial organelles, and describes the development of an artificial endoplasmic reticulum and Golgi organelle on a digita...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2010.95 |
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| _version_ | 1832552088572264448 |
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| author | Jeffrey G. Martin Julie M. Beaudet Jonathan S. Dordick Robert J. Linhardt |
| author_facet | Jeffrey G. Martin Julie M. Beaudet Jonathan S. Dordick Robert J. Linhardt |
| author_sort | Jeffrey G. Martin |
| collection | DOAJ |
| description | The development of artificial organelles is a new, fast-growing field in which a variety of techniques have been employed. This article gives a brief overview of the history of artificial organelles, and describes the development of an artificial endoplasmic reticulum and Golgi organelle on a digital microfluidic platform. This device should be useful in high-throughput combinatorial proteoglycan/glycoprotein synthesis, providing critical information about the control of biosynthetic pathways for these important signaling molecules. |
| format | Article |
| id | doaj-art-87419d3f32824d1cbd1281de95bb71d4 |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-87419d3f32824d1cbd1281de95bb71d42025-02-03T05:59:40ZengWileyThe Scientific World Journal1537-744X2010-01-0110997100010.1100/tsw.2010.95Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein BiosynthesisJeffrey G. Martin0Julie M. Beaudet1Jonathan S. Dordick2Robert J. Linhardt3Department of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Center for Biotechnology and Interdisciplinary Studies, Troy, NY, USADepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Center for Biotechnology and Interdisciplinary Studies, Troy, NY, USADepartment of Biology, Rensselaer Polytechnic Institute, Center for Biotechnology and Interdisciplinary Studies, Troy, NY, USADepartment of Chemistry and Chemical Biology, Rensselaer Polytechnic Institute, Center for Biotechnology and Interdisciplinary Studies, Troy, NY, USAThe development of artificial organelles is a new, fast-growing field in which a variety of techniques have been employed. This article gives a brief overview of the history of artificial organelles, and describes the development of an artificial endoplasmic reticulum and Golgi organelle on a digital microfluidic platform. This device should be useful in high-throughput combinatorial proteoglycan/glycoprotein synthesis, providing critical information about the control of biosynthetic pathways for these important signaling molecules.http://dx.doi.org/10.1100/tsw.2010.95 |
| spellingShingle | Jeffrey G. Martin Julie M. Beaudet Jonathan S. Dordick Robert J. Linhardt Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis The Scientific World Journal |
| title | Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis |
| title_full | Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis |
| title_fullStr | Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis |
| title_full_unstemmed | Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis |
| title_short | Artificial Organelles: Digital Microfluidic Platform for Proteoglycan and Glycoprotein Biosynthesis |
| title_sort | artificial organelles digital microfluidic platform for proteoglycan and glycoprotein biosynthesis |
| url | http://dx.doi.org/10.1100/tsw.2010.95 |
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