Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine

Background Context. Up to date, only four cases of primary intradural extramedullary spinal cord melanoma (PIEM) have been reported. No previous reports have described a case of PIEM located in the lower thoracic spine with long-term follow-up. Purpose. Demonstrating an unusual, extremely rare case...

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Main Authors: Kathrin Hering, Anke Bresch, Donald Lobsien, Wolf Mueller, Rolf-Dieter Kortmann, Clemens Seidel
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Oncological Medicine
Online Access:http://dx.doi.org/10.1155/2016/3815280
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author Kathrin Hering
Anke Bresch
Donald Lobsien
Wolf Mueller
Rolf-Dieter Kortmann
Clemens Seidel
author_facet Kathrin Hering
Anke Bresch
Donald Lobsien
Wolf Mueller
Rolf-Dieter Kortmann
Clemens Seidel
author_sort Kathrin Hering
collection DOAJ
description Background Context. Up to date, only four cases of primary intradural extramedullary spinal cord melanoma (PIEM) have been reported. No previous reports have described a case of PIEM located in the lower thoracic spine with long-term follow-up. Purpose. Demonstrating an unusual, extremely rare case of melanoma manifestation. Study Design. Case report. Methods. We report a case of a 57-year-old female suffering from increasing lower extremity pain, left-sided paresis, and paraesthesia due to spinal cord compression caused by PIEM in the lower thoracic spine. Results. Extensive investigation excluded other possible primary melanoma sites and metastases. For spinal cord decompression, the tumor at level T12 was resected, yet incompletely. Adjuvant radiotherapy was administered two weeks after surgery. The patient was recurrence-free at 104 weeks after radiotherapy but presents with unchanged neurological symptoms. Conclusion. Primary intradural extramedullary melanoma (PIEM) is extremely rare and its clinical course is unpredictable.
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spelling doaj-art-87385cf238f94a8f87598936621657192025-02-03T05:44:28ZengWileyCase Reports in Oncological Medicine2090-67062090-67142016-01-01201610.1155/2016/38152803815280Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic SpineKathrin Hering0Anke Bresch1Donald Lobsien2Wolf Mueller3Rolf-Dieter Kortmann4Clemens Seidel5Department of Radiotherapy and Radiation Oncology, Leipzig University, Liebigstrasse 20, 04103 Leipzig, GermanyDepartment of Nuclear Medicine, Leipzig University, Liebigstrasse 20, 04103 Leipzig, GermanyDepartment of Neuroradiology, Leipzig University, Liebigstrasse 20, 04103 Leipzig, GermanyDepartment of Neuropathology, Leipzig University, Liebigstrasse 20, 04103 Leipzig, GermanyDepartment of Radiotherapy and Radiation Oncology, Leipzig University, Liebigstrasse 20, 04103 Leipzig, GermanyDepartment of Radiotherapy and Radiation Oncology, Leipzig University, Liebigstrasse 20, 04103 Leipzig, GermanyBackground Context. Up to date, only four cases of primary intradural extramedullary spinal cord melanoma (PIEM) have been reported. No previous reports have described a case of PIEM located in the lower thoracic spine with long-term follow-up. Purpose. Demonstrating an unusual, extremely rare case of melanoma manifestation. Study Design. Case report. Methods. We report a case of a 57-year-old female suffering from increasing lower extremity pain, left-sided paresis, and paraesthesia due to spinal cord compression caused by PIEM in the lower thoracic spine. Results. Extensive investigation excluded other possible primary melanoma sites and metastases. For spinal cord decompression, the tumor at level T12 was resected, yet incompletely. Adjuvant radiotherapy was administered two weeks after surgery. The patient was recurrence-free at 104 weeks after radiotherapy but presents with unchanged neurological symptoms. Conclusion. Primary intradural extramedullary melanoma (PIEM) is extremely rare and its clinical course is unpredictable.http://dx.doi.org/10.1155/2016/3815280
spellingShingle Kathrin Hering
Anke Bresch
Donald Lobsien
Wolf Mueller
Rolf-Dieter Kortmann
Clemens Seidel
Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine
Case Reports in Oncological Medicine
title Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine
title_full Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine
title_fullStr Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine
title_full_unstemmed Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine
title_short Primary Intradural Extramedullary Spinal Melanoma in the Lower Thoracic Spine
title_sort primary intradural extramedullary spinal melanoma in the lower thoracic spine
url http://dx.doi.org/10.1155/2016/3815280
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