Protective Effects of <i>Physalis angulata</i> on Podocythopathies Through B-Cell-Activating Factor Inhibition in Doxorubicin-Induced Nephrotic Syndrome Rat Model

Protective Effects of <i>Physalis angulata</i> on Podocythopathies Through B-Cell-Activating Factor Inhibition in Doxorubicin-Induced Nephrotic Syndrome Rat Model

<b>Background/Objectives</b>: Nephrotic syndrome, a glomerular disease caused by podocyte dysfunction, is characterized by proteinuria, hypoalbuminemia, edema, and hyperlipidemia. Current treatment relies on corticosteroids, which carry the risk of long-term side effects. <i>Physal...

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Bibliographic Details
Main Authors: Astrid K. Kardani, Loeki E. Fitri, Nur Samsu, Krisni Subandiyah
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
nephrotic syndrome
<i>Physalis angulata</i>
BAFF
podocalyxin
nephrin
GLEPP-1
Online Access:https://www.mdpi.com/2227-9059/13/3/719
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