Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

BackgroundZingiber officinale Roscoe has been shown to possess analgesic properties. Zingerone (ZO), a bioactive compound derived from Zingiber officinale Roscoe, exhibits a range of pharmacological effects, including anti-inflammatory, anti-cancer, antioxidant, antibacterial, and anti-apoptotic act...

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Bibliographic Details
Main Authors: Yuanyuan Wang, Lang Dong, Shu Han, Yuehan You, Mingrui Zhang, Bingjing Sun, Hong Ni, Rongjing Ge, Jianhong Liu, Jiandong Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
Zingiber officinale roscoe
analgesic
intrinsic excitability
complete Freund’s adjuvant (CFA)
refractory period
electrophysiological
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1543594/full
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