Metformin Increases Serum Isthmin-1 Levels and Lowers Low-Density Lipoprotein: Potential Implications for Lipid Metabolism in T2DM

Metformin Increases Serum Isthmin-1 Levels and Lowers Low-Density Lipoprotein: Potential Implications for Lipid Metabolism in T2DM

<i>Background and Objectives:</i> Type 2 Diabetes Mellitus (T2DM) is a metabolic disease caused by the failure of the skeletal muscle, liver and adipose tissue to respond to insulin. Metformin is the first choice for the treatment of T2DM. Isthmin 1 (Ism1) is a newly discovered adipokine...

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Bibliographic Details
Main Authors: Merve Yilmaz Bozoglan, Tuncay Kuloglu, Nevzat Gozel, Faruk Kılınc, Erkan Cakmak, Ramazan Fazıl Akkoç, Betül Dağoğlu Hark
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Medicina
Subjects:
adipokine
isthmin 1
metformin
T2DM
LDL
Online Access:https://www.mdpi.com/1648-9144/61/3/522
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