Diphencyprone Induced Vitiligo: A Case Report
Diphencyprone (DCP) is a contact sensitizer which is used to treat dermatological disorders with an immunological origin, such as extensive alopecia areata (AA). Vitiligo is a rare but known side effect of DPCP therapy which is formed in the treatment site or remote areas. In this paper a 37-year-ol...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/356236 |
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| author | Mohammad Ali Nilforoushzadeh Gelavizh Keshtmand Fariba Jaffary Abbas Kheirkhah |
| author_facet | Mohammad Ali Nilforoushzadeh Gelavizh Keshtmand Fariba Jaffary Abbas Kheirkhah |
| author_sort | Mohammad Ali Nilforoushzadeh |
| collection | DOAJ |
| description | Diphencyprone (DCP) is a contact sensitizer which is used to treat dermatological disorders with an immunological origin, such as extensive alopecia areata (AA). Vitiligo is a rare but known side effect of DPCP therapy which is formed in the treatment site or remote areas. In this paper a 37-year-old man developed alopecia totalis with loss of eyebrows and eyelashes who presented some vitiligo patches on his scalp and arm distant from the location of DPCP application and a 42-year-old woman with 25 years history of hair loss and 3 months DPCP application who revealed some vitiligo patches on the scalp with distant to the site of application at the 6th week are reported. Considering the absence of personal and family history of Vitiligo in our two cases, the hypothesis of latent Vitiligo is not proved. The positive patch test in left arm of one of the patients also suggests the direct role of DPCP as the cause of Vitiligo occurrence. As the development of vitiligo by DCP is unpredictable and the depigmentation may persist indefinitely, it is important to inform all patients about this potential adverse effect before starting the treatment. |
| format | Article |
| id | doaj-art-86edaac9939e4780868188898c12d3fb |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-86edaac9939e4780868188898c12d3fb2025-02-03T01:23:42ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/356236356236Diphencyprone Induced Vitiligo: A Case ReportMohammad Ali Nilforoushzadeh0Gelavizh Keshtmand1Fariba Jaffary2Abbas Kheirkhah3Skin and Stem cell Research Center, Tehran University of Medical Sciences, Tehran 19377957511, IranSkin and Stem cell Research Center, Tehran University of Medical Sciences, Tehran 19377957511, IranSkin and Stem cell Research Center, Tehran University of Medical Sciences, Tehran 19377957511, IranSkin and Stem cell Research Center, Tehran University of Medical Sciences, Tehran 19377957511, IranDiphencyprone (DCP) is a contact sensitizer which is used to treat dermatological disorders with an immunological origin, such as extensive alopecia areata (AA). Vitiligo is a rare but known side effect of DPCP therapy which is formed in the treatment site or remote areas. In this paper a 37-year-old man developed alopecia totalis with loss of eyebrows and eyelashes who presented some vitiligo patches on his scalp and arm distant from the location of DPCP application and a 42-year-old woman with 25 years history of hair loss and 3 months DPCP application who revealed some vitiligo patches on the scalp with distant to the site of application at the 6th week are reported. Considering the absence of personal and family history of Vitiligo in our two cases, the hypothesis of latent Vitiligo is not proved. The positive patch test in left arm of one of the patients also suggests the direct role of DPCP as the cause of Vitiligo occurrence. As the development of vitiligo by DCP is unpredictable and the depigmentation may persist indefinitely, it is important to inform all patients about this potential adverse effect before starting the treatment.http://dx.doi.org/10.1155/2012/356236 |
| spellingShingle | Mohammad Ali Nilforoushzadeh Gelavizh Keshtmand Fariba Jaffary Abbas Kheirkhah Diphencyprone Induced Vitiligo: A Case Report Case Reports in Medicine |
| title | Diphencyprone Induced Vitiligo: A Case Report |
| title_full | Diphencyprone Induced Vitiligo: A Case Report |
| title_fullStr | Diphencyprone Induced Vitiligo: A Case Report |
| title_full_unstemmed | Diphencyprone Induced Vitiligo: A Case Report |
| title_short | Diphencyprone Induced Vitiligo: A Case Report |
| title_sort | diphencyprone induced vitiligo a case report |
| url | http://dx.doi.org/10.1155/2012/356236 |
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