Anticancer effects of 7,8-dihydromethysticin in human leukemia cells are mediated via cell-cycle dysregulation, inhibition of cell migration and invasion and targeting JAK/STAT pathway
The main focus of this research work was to study the anti-cancer properties of 7,8-dihydromethysticin against HL-60 leukemia cells. Investigations were also performed to check its impact on the phases of the cell cycle, cell migration and invasion, JAK/STAT signalling pathway and intracellular mito...
Saved in:
Main Authors: | Xiao Yi, Deng Taoran, Jiang Lijun, Wang Di |
---|---|
Format: | Article |
Language: | English |
Published: |
Sciendo
2021-12-01
|
Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2021-0037 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
CD9 in acute myeloid leukemia: Prognostic role and usefulness to target leukemic stem cells
by: Lucas Touzet, et al.
Published: (2019-03-01) -
STAT signaling in the pathogenesis and therapy of acute myeloid leukemia and myelodysplastic syndromes
by: Zoe King, et al.
Published: (2025-03-01) -
Concentration-dependent effects of immunomodulatory cocktails on the generation of leukemia-derived dendritic cells, DCleu mediated T-cell activation and on-target/off-tumor toxicity
by: Hazal Aslan Rejeski, et al.
Published: (2025-01-01) -
Post-injury treatment with 7,8-dihydroxyflavone attenuates white matter pathology in aged mice following focal traumatic brain injury
by: Georgios Michalettos, et al.
Published: (2025-01-01) -
Metabolic adaptations to acute glucose uptake inhibition converge upon mitochondrial respiration for leukemia cell survival
by: Monika Komza, et al.
Published: (2025-01-01)