Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis

Periplanta americana extract regulates the Th17/Treg cell balance via Notch1 in ulcerative colitis

BackgroundPeriplanta americana extract (PAE), a traditional Chinese medicine (TCM) from Shen Nong Ben Cao Jing, has been used to treat ulcerative colitis (UC), various types of wounds and ulcers, infantile malnutrition, palpitation, asthma, and so on. However, the exact mechanisms of PAE in UC have...

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Bibliographic Details
Main Authors: Yanqiu Zheng, Huibiao Li, Shiyu Qi, Fan Xiao, Jinbin Song, Shiyin Liu, Xinlin Chen, Yanwu Li, Muyuan Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
ulcerative colitis
Periplaneta americana extract
Th17/Treg
Notch1
colonic mucosa
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1534772/full
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https://www.frontiersin.org/articles/10.3389/fphar.2024.1534772/full

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