Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes

Abstract In this study, Nile tilapia were fed a blend of oilseed meals (BOM) that includes cottonseed meal (CSM), linseed meal (LSM), sesame meal (SSM), and sunflower meal (SFM) at a ratio of 1 CSM: 1 LSM: 1 SSM: 1 SFM. Six diets were formulated where the first diet included FM and SBM as protein so...

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Main Authors: Ahmed A. Badran, Fawzy I. Magouz, Amr I. Zaineldin, Safaa E. Abdo, Asem A. Amer, Mahmoud S. Gewaily, Mahmoud A.O. Dawood
Format: Article
Language:English
Published: BMC 2024-11-01
Series:BMC Veterinary Research
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Online Access:https://doi.org/10.1186/s12917-024-04373-5
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author Ahmed A. Badran
Fawzy I. Magouz
Amr I. Zaineldin
Safaa E. Abdo
Asem A. Amer
Mahmoud S. Gewaily
Mahmoud A.O. Dawood
author_facet Ahmed A. Badran
Fawzy I. Magouz
Amr I. Zaineldin
Safaa E. Abdo
Asem A. Amer
Mahmoud S. Gewaily
Mahmoud A.O. Dawood
author_sort Ahmed A. Badran
collection DOAJ
description Abstract In this study, Nile tilapia were fed a blend of oilseed meals (BOM) that includes cottonseed meal (CSM), linseed meal (LSM), sesame meal (SSM), and sunflower meal (SFM) at a ratio of 1 CSM: 1 LSM: 1 SSM: 1 SFM. Six diets were formulated where the first diet included FM and SBM as protein sources and considered the positive control diet (FM). Another five FM-free diets were formulated, where SBM was substituted with BOM and included at 0, 100, 200, 300, and 400 g/kg diet. After 90 days, the FBW, WG, and PER were markedly increased while FCR decreased by FM-based diet and BOM at 0, 100, or 200 g/kg compared to fish-fed BOM at 300, and 400 g/kg (P < 0.05). The groups treated with BOM at 100–200 g/kg demonstrated considerable impairments, followed by those treated with BOM at 300 g/kg. Furthermore, fish given BOM at 400 g/kg had significantly less intestinal histological characteristics than the other groups. The relative expression of the IGF-1, GHR1, FABP, and CCK genes were downregulated in tilapia-fed BOM at 200, 300, and 400 g/kg compared to fish-fed FM-based diet (P < 0.05). The relative cost of feed per kg fish gain showed 4.42, 7.11, 8.14, 10.32, and 8.10% reduction rates in fish-fed SBM, or BOM at 100, 200, 300, and 400 g/kg. In conclusion, dietary BOM can be incorporated in Nile tilapia diets at up to 200 g/kg without affecting growth performance or feed utilisation. High inclusion levels (300 and 400 g/kg) may impair growth performance and feed utilisation by disrupting intestinal histological characteristics and reducing expression of growth and metabolic genes (GHR1, IGF-1, FABP, and CCK) in the liver.
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spelling doaj-art-86949c5655c84a4bbb3e28734c5d3f6b2025-08-20T02:08:23ZengBMCBMC Veterinary Research1746-61482024-11-0120111410.1186/s12917-024-04373-5Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genesAhmed A. Badran0Fawzy I. Magouz1Amr I. Zaineldin2Safaa E. Abdo3Asem A. Amer4Mahmoud S. Gewaily5Mahmoud A.O. Dawood6Animal Production Department, Faculty of Agriculture, Kafrelsheikh UniversityAnimal Production Department, Faculty of Agriculture, Kafrelsheikh UniversityUnit of Biochemistry, Nutritional Deficiency Diseases and Toxicology, Agriculture Research Center, Animal Health Research Institute (AHRI-DOKI)Genetics and Genetic Engineering, Department of Animal Wealth Development, Faculty of Veterinary Medicine, Kafrelsheikh UniversityDepartment of Fish Nutrition and Feed Technology, Central Laboratory for Aquaculture Research, Agricultural Research CenterDepartment of Anatomy and Embryology, Faculty of Veterinary Medicine, Kafrelsheikh UniversityAnimal Production Department, Faculty of Agriculture, Kafrelsheikh UniversityAbstract In this study, Nile tilapia were fed a blend of oilseed meals (BOM) that includes cottonseed meal (CSM), linseed meal (LSM), sesame meal (SSM), and sunflower meal (SFM) at a ratio of 1 CSM: 1 LSM: 1 SSM: 1 SFM. Six diets were formulated where the first diet included FM and SBM as protein sources and considered the positive control diet (FM). Another five FM-free diets were formulated, where SBM was substituted with BOM and included at 0, 100, 200, 300, and 400 g/kg diet. After 90 days, the FBW, WG, and PER were markedly increased while FCR decreased by FM-based diet and BOM at 0, 100, or 200 g/kg compared to fish-fed BOM at 300, and 400 g/kg (P < 0.05). The groups treated with BOM at 100–200 g/kg demonstrated considerable impairments, followed by those treated with BOM at 300 g/kg. Furthermore, fish given BOM at 400 g/kg had significantly less intestinal histological characteristics than the other groups. The relative expression of the IGF-1, GHR1, FABP, and CCK genes were downregulated in tilapia-fed BOM at 200, 300, and 400 g/kg compared to fish-fed FM-based diet (P < 0.05). The relative cost of feed per kg fish gain showed 4.42, 7.11, 8.14, 10.32, and 8.10% reduction rates in fish-fed SBM, or BOM at 100, 200, 300, and 400 g/kg. In conclusion, dietary BOM can be incorporated in Nile tilapia diets at up to 200 g/kg without affecting growth performance or feed utilisation. High inclusion levels (300 and 400 g/kg) may impair growth performance and feed utilisation by disrupting intestinal histological characteristics and reducing expression of growth and metabolic genes (GHR1, IGF-1, FABP, and CCK) in the liver.https://doi.org/10.1186/s12917-024-04373-5AquafeedAlternative ingredientsDigestionMetabolismTilapia
spellingShingle Ahmed A. Badran
Fawzy I. Magouz
Amr I. Zaineldin
Safaa E. Abdo
Asem A. Amer
Mahmoud S. Gewaily
Mahmoud A.O. Dawood
Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes
BMC Veterinary Research
Aquafeed
Alternative ingredients
Digestion
Metabolism
Tilapia
title Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes
title_full Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes
title_fullStr Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes
title_full_unstemmed Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes
title_short Using a blend of oilseed meals in the diets of Nile tilapia (Oreochromis niloticus): effects on the growth performance, feed utilization, intestinal health, growth, and metabolic-related genes
title_sort using a blend of oilseed meals in the diets of nile tilapia oreochromis niloticus effects on the growth performance feed utilization intestinal health growth and metabolic related genes
topic Aquafeed
Alternative ingredients
Digestion
Metabolism
Tilapia
url https://doi.org/10.1186/s12917-024-04373-5
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