The Drosophila DEG/ENaC PPK12 is a Na+ leak channel with a low Na+ affinity

The Drosophila DEG/ENaC PPK12 is a Na+ leak channel with a low Na+ affinity

Abstract DEG/ENaC ion channels have various functions in different organisms. In Drosophila, DEG/ENaCs are named Pickpockets (PPKs) and form a large insect-specific radiation with seven subfamilies containing 31 members. Several different functions have been proposed for PPKs, including salt and wat...

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Bibliographic Details
Main Authors: Lu Qin, Nikita Komarov, Cornelia Fritsch, Simon G. Sprecher, Stefan Gründer, Dominik Wiemuth
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Ion channel
Larvae
Salt sensation
Taste
Online Access:https://doi.org/10.1038/s41598-025-10609-7
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