TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research
Given that angiogenesis and lymphangiogenesis are strongly related to prognosis in neoplastic and other pathologies and that many methods exist that provide different results, we aim to construct a morphometric tool allowing us to measure different aspects of the shape and size of vascular vessels i...
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Format: | Article |
Language: | English |
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Wiley
2013-01-01
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Series: | The Scientific World Journal |
Online Access: | http://dx.doi.org/10.1155/2013/263190 |
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author | M. Milagro Fernández-Carrobles Irene Tadeo Gloria Bueno Rosa Noguera Oscar Déniz Jesús Salido Marcial García-Rojo |
author_facet | M. Milagro Fernández-Carrobles Irene Tadeo Gloria Bueno Rosa Noguera Oscar Déniz Jesús Salido Marcial García-Rojo |
author_sort | M. Milagro Fernández-Carrobles |
collection | DOAJ |
description | Given that angiogenesis and lymphangiogenesis are strongly related to prognosis in neoplastic and other pathologies and that many methods exist that provide different results, we aim to construct a morphometric tool allowing us to measure different aspects of the shape and size of vascular vessels in a complete and accurate way. The developed tool presented is based on vessel closing which is an essential property to properly characterize the size and the shape of vascular and lymphatic vessels. The method is fast and accurate improving existing tools for angiogenesis analysis. The tool also improves the accuracy of vascular density measurements, since the set of endothelial cells forming a vessel is considered as a single object. |
format | Article |
id | doaj-art-868148da0fbc4edb801447e00638646d |
institution | Kabale University |
issn | 1537-744X |
language | English |
publishDate | 2013-01-01 |
publisher | Wiley |
record_format | Article |
series | The Scientific World Journal |
spelling | doaj-art-868148da0fbc4edb801447e00638646d2025-02-03T01:20:42ZengWileyThe Scientific World Journal1537-744X2013-01-01201310.1155/2013/263190263190TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis ResearchM. Milagro Fernández-Carrobles0Irene Tadeo1Gloria Bueno2Rosa Noguera3Oscar Déniz4Jesús Salido5Marcial García-Rojo6VISILAB, E.T.S.I. Industriales, Universidad de Castilla-La Mancha, 13071 Ciudad Real, SpainFundación Investigación Clínico de Valencia, Instituto de Investigación Sanitaria, INCLIVA, 46010 Valencia, SpainVISILAB, E.T.S.I. Industriales, Universidad de Castilla-La Mancha, 13071 Ciudad Real, SpainLaboratorio de Patología Molecular, Departmento de Patología, Facultad de Medicina y Odontología, Universidad de Valencia, 46010 Valencia, SpainVISILAB, E.T.S.I. Industriales, Universidad de Castilla-La Mancha, 13071 Ciudad Real, SpainVISILAB, E.T.S.I. Industriales, Universidad de Castilla-La Mancha, 13071 Ciudad Real, SpainDepartmento de Anatomía Patológica, Hospital General Universitario de Ciudad Real, 13005 Ciudad Real, SpainGiven that angiogenesis and lymphangiogenesis are strongly related to prognosis in neoplastic and other pathologies and that many methods exist that provide different results, we aim to construct a morphometric tool allowing us to measure different aspects of the shape and size of vascular vessels in a complete and accurate way. The developed tool presented is based on vessel closing which is an essential property to properly characterize the size and the shape of vascular and lymphatic vessels. The method is fast and accurate improving existing tools for angiogenesis analysis. The tool also improves the accuracy of vascular density measurements, since the set of endothelial cells forming a vessel is considered as a single object.http://dx.doi.org/10.1155/2013/263190 |
spellingShingle | M. Milagro Fernández-Carrobles Irene Tadeo Gloria Bueno Rosa Noguera Oscar Déniz Jesús Salido Marcial García-Rojo TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research The Scientific World Journal |
title | TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research |
title_full | TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research |
title_fullStr | TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research |
title_full_unstemmed | TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research |
title_short | TMA Vessel Segmentation Based on Color and Morphological Features: Application to Angiogenesis Research |
title_sort | tma vessel segmentation based on color and morphological features application to angiogenesis research |
url | http://dx.doi.org/10.1155/2013/263190 |
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