microRNA-576-5p ameliorates dexamethasone-induced BMSC injury by suppressing ANXA2

microRNA-576-5p ameliorates dexamethasone-induced BMSC injury by suppressing ANXA2

Abstract Dysfunction of Bone Marrow Derived Mesenchymal Stem Cells (BMSCs) induced by glucocorticoids has been identified as a key pathological mechanism of steroid-induced osteonecrosis of the femoral head (SONFH). Consequently, restoring the function of BMSCs is a vital strategy for treating SONFH...

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Bibliographic Details
Main Authors: Yuelei Zhang, Ying Deng, Weihai Yao, Ke Xia, Lecheng Zhang, Gang Wang
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
MiR-576-5p
ANXA2
Steroid-induced osteonecrosis of the femoral head
Glucocorticoid
Dexamethasone
Bone marrow derived mesenchymal stem cell
Online Access:https://doi.org/10.1038/s41598-025-16883-9
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