Low‐Intensity Focused Ultrasound‐Responsive, Phase‐Change Nanodroplets to Remodel Macrophage Polarization and Enhance PD‐L1 Blockade Therapy

Low‐Intensity Focused Ultrasound‐Responsive, Phase‐Change Nanodroplets to Remodel Macrophage Polarization and Enhance PD‐L1 Blockade Therapy

Immune checkpoint blockade (ICB) therapy is a promising treatment that has shown significant effects in certain refractory and advanced cancers. However, not all patients respond to ICB therapy. The tumor microenvironment (TME) helps tumors evade immune surveillance and attack, contributing to the l...

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Main Authors: Qin Zhang, Ci Yin, Junjie Liu, Hua Yang, Yanping Zhang, Qiaoxi Qin, Nianhong Wu, Rui Tang, Yuting Cao, Min Zheng, Hongye He, Hongmei Dong, Yang Zhou, Jianli Ren, Zhengju Ren, Pan Li
Format: Article
Language:English
Published: Wiley-VCH 2025-04-01
Series:Small Structures
Subjects:
immune checkpoint blocking therapy
low‐intensity focused ultrasound
nanodroplets
tumor microenvironment
tumor‐associated macrophages
Online Access:https://doi.org/10.1002/sstr.202400441
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