Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy
Diarrhea is one of the most common complications following colectomy in patients with slow transit constipation (STC). Early postoperative diarrhea is usually treated with opioid agonists; however, to date, published data on the management of persistent diarrhea after colectomy for STC are scarce. H...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/686120 |
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| author | Patrick Schoeters Karl De Pooter |
| author_facet | Patrick Schoeters Karl De Pooter |
| author_sort | Patrick Schoeters |
| collection | DOAJ |
| description | Diarrhea is one of the most common complications following colectomy in patients with slow transit constipation (STC). Early postoperative diarrhea is usually treated with opioid agonists; however, to date, published data on the management of persistent diarrhea after colectomy for STC are scarce. Here, we report a case of severe diarrhea after a total colectomy with ileorectal anastomosis. One year after the surgery, the patient presented with persistent diarrhea. Treatment with a long-acting somatostatin analogue, lanreotide Autogel, was initiated. One month after the first injection of lanreotide Autogel the diarrhea was resolved. The patient’s stool transit was markedly improved (type 4 or type 5 according to the Bristol Stool Chart compared to type 7 before the treatment), positively affecting the patient’s quality of life (mean score of 2.1 on the Irritable Bowel Syndrome Quality of Life questionnaire compared to 3.9 before the treatment). This case report describes a successful use of lanreotide Autogel in a patient with persistent diarrhea after a total colectomy. |
| format | Article |
| id | doaj-art-8640e88a0a2a41b392e0186018434ea8 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-8640e88a0a2a41b392e0186018434ea82025-02-03T05:59:01ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362015-01-01201510.1155/2015/686120686120Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total ColectomyPatrick Schoeters0Karl De Pooter1Department of Gastroenterology, AZ Herentals, 2200 Herentals, BelgiumDepartment of Gastrointestinal Surgery, AZ Herentals, 2200 Herentals, BelgiumDiarrhea is one of the most common complications following colectomy in patients with slow transit constipation (STC). Early postoperative diarrhea is usually treated with opioid agonists; however, to date, published data on the management of persistent diarrhea after colectomy for STC are scarce. Here, we report a case of severe diarrhea after a total colectomy with ileorectal anastomosis. One year after the surgery, the patient presented with persistent diarrhea. Treatment with a long-acting somatostatin analogue, lanreotide Autogel, was initiated. One month after the first injection of lanreotide Autogel the diarrhea was resolved. The patient’s stool transit was markedly improved (type 4 or type 5 according to the Bristol Stool Chart compared to type 7 before the treatment), positively affecting the patient’s quality of life (mean score of 2.1 on the Irritable Bowel Syndrome Quality of Life questionnaire compared to 3.9 before the treatment). This case report describes a successful use of lanreotide Autogel in a patient with persistent diarrhea after a total colectomy.http://dx.doi.org/10.1155/2015/686120 |
| spellingShingle | Patrick Schoeters Karl De Pooter Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy Case Reports in Gastrointestinal Medicine |
| title | Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy |
| title_full | Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy |
| title_fullStr | Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy |
| title_full_unstemmed | Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy |
| title_short | Lanreotide Autogel in the Treatment of Persistent Diarrhea following a Total Colectomy |
| title_sort | lanreotide autogel in the treatment of persistent diarrhea following a total colectomy |
| url | http://dx.doi.org/10.1155/2015/686120 |
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