Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review
Malignant pilomatricoma, an extremely rare tumor arising from hair follicles, most commonly occurs on the head, neck, and back. This tumor exhibits several noteworthy characteristics. First, it frequently recurs if it is incompletely excised and can occasionally metastasize to the lungs, bones, and...
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| Format: | Article |
| Language: | English |
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Thieme Medical Publishers, Inc.
2025-01-01
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| Series: | Archives of Plastic Surgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1792022 |
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| author | Nae-Ho Lee Jung Kyun Park Si-Gyun Roh Jin Yong Shin Yoon Kyu Chung Kyu Yun Jang |
| author_facet | Nae-Ho Lee Jung Kyun Park Si-Gyun Roh Jin Yong Shin Yoon Kyu Chung Kyu Yun Jang |
| author_sort | Nae-Ho Lee |
| collection | DOAJ |
| description | Malignant pilomatricoma, an extremely rare tumor arising from hair follicles, most commonly occurs on the head, neck, and back. This tumor exhibits several noteworthy characteristics. First, it frequently recurs if it is incompletely excised and can occasionally metastasize to the lungs, bones, and lymph nodes. Additionally, it possesses unique histological features that aid in differentiating it from its benign counterpart, including atypical cells, multiple mitoses with ghost cells, nuclear polymorphisms, and necrosis accompanied by serial desmoplasia. While no definitive criteria have been established for the surgical management of this malignant tumor, it is recommended to perform wide local excision with a safety margin of at least ≥5 mm. To the best of our knowledge, very few cases of malignant pilomatricoma with lung metastasis have been reported in Korea. Here we report the case of a patient diagnosed of malignant pilomatricoma with lung metastasis who underwent wide local excision for a lesion on the flank. |
| format | Article |
| id | doaj-art-8635d87050724b789ad4661c1ac8c040 |
| institution | Kabale University |
| issn | 2234-6163 2234-6171 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Archives of Plastic Surgery |
| spelling | doaj-art-8635d87050724b789ad4661c1ac8c0402025-01-21T23:42:09ZengThieme Medical Publishers, Inc.Archives of Plastic Surgery2234-61632234-61712025-01-01520102102410.1055/s-0044-1792022Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature ReviewNae-Ho Lee0https://orcid.org/0000-0003-1354-8203Jung Kyun Park1https://orcid.org/0009-0009-0690-7088Si-Gyun Roh2https://orcid.org/0000-0003-2865-0075Jin Yong Shin3https://orcid.org/0000-0003-2680-7411Yoon Kyu Chung4https://orcid.org/0000-0002-0401-3912Kyu Yun Jang5https://orcid.org/0000-0002-5276-4446Department of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of KoreaDepartment of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of KoreaDepartment of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of KoreaDepartment of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of KoreaDepartment of Plastic and Reconstructive Surgery, Medical School of Jeonbuk National University, Jeonju, Republic of KoreaDepartment of Pathology, Medical School of Jeonbuk National University, Jeonju, Republic of KoreaMalignant pilomatricoma, an extremely rare tumor arising from hair follicles, most commonly occurs on the head, neck, and back. This tumor exhibits several noteworthy characteristics. First, it frequently recurs if it is incompletely excised and can occasionally metastasize to the lungs, bones, and lymph nodes. Additionally, it possesses unique histological features that aid in differentiating it from its benign counterpart, including atypical cells, multiple mitoses with ghost cells, nuclear polymorphisms, and necrosis accompanied by serial desmoplasia. While no definitive criteria have been established for the surgical management of this malignant tumor, it is recommended to perform wide local excision with a safety margin of at least ≥5 mm. To the best of our knowledge, very few cases of malignant pilomatricoma with lung metastasis have been reported in Korea. Here we report the case of a patient diagnosed of malignant pilomatricoma with lung metastasis who underwent wide local excision for a lesion on the flank.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1792022malignant pilomatricomalung metastasiscase reports |
| spellingShingle | Nae-Ho Lee Jung Kyun Park Si-Gyun Roh Jin Yong Shin Yoon Kyu Chung Kyu Yun Jang Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review Archives of Plastic Surgery malignant pilomatricoma lung metastasis case reports |
| title | Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review |
| title_full | Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review |
| title_fullStr | Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review |
| title_full_unstemmed | Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review |
| title_short | Malignant Pilomatricoma with Lung Metastases: A Case Report and Literature Review |
| title_sort | malignant pilomatricoma with lung metastases a case report and literature review |
| topic | malignant pilomatricoma lung metastasis case reports |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0044-1792022 |
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