Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma.

Unraveling regulatory programs for NF-kappaB, p53 and microRNAs in head and neck squamous cell carcinoma.

In head and neck squamous cell carcinoma (HNSCC), mutations of p53 usually coexist with aberrant activation of NF-kappaB (NF-κB), other transcription factors and microRNAs, which promote tumor pathogenesis. However, how these factors and microRNAs interact to globally modulate gene expression and me...

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Bibliographic Details
Main Authors: Bin Yan, Huai Li, Xinping Yang, Jiaofang Shao, Minyoung Jang, Daogang Guan, Sige Zou, Carter Van Waes, Zhong Chen, Ming Zhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0073656
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