Cepacia Syndrome in a Non-Cystic Fibrosis Patient
Burkholderia (formerly Pseudomonas) cepacia complex is a known serious threat to patients with cystic fibrosis, in whom it has the potential to cause the fatal combination of necrotizing pneumonia, worsening respiratory failure, and bacteremia, known as Cepacia syndrome. The potential for this patho...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2015/537627 |
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| author | Naomi Hauser Jose Orsini |
| author_facet | Naomi Hauser Jose Orsini |
| author_sort | Naomi Hauser |
| collection | DOAJ |
| description | Burkholderia (formerly Pseudomonas) cepacia complex is a known serious threat to patients with cystic fibrosis, in whom it has the potential to cause the fatal combination of necrotizing pneumonia, worsening respiratory failure, and bacteremia, known as Cepacia syndrome. The potential for this pathogen to infect non-cystic fibrosis patients is limited and its epidemiology is poorly understood. Previously reported cases of severe Burkholderia cepacia complex lung infection in immunocompetent hosts include pneumonia, bronchiectasis, pyopneumothorax, and cavitary lesions. We present a case of a 64-year-old man with Streptococcus pneumoniae community-acquired pneumonia whose hospital course was complicated by developing cavitary lung lesions, bacteremia, and acute respiratory distress syndrome. Repeated tracheal aspirate and blood cultures grew Burkholderia cepacia. Our case appears to be the first report of Cepacia syndrome in a patient without cystic fibrosis. This report raises concern regarding the potential severity of pulmonary Burkholderia cepacia complex infection and the need to broaden clinicians’ suspicion for Cepacia syndrome. A framework to help diagnose and treat infected non-cystic fibrosis individuals may be useful. |
| format | Article |
| id | doaj-art-861c900cf808420d8d5b98ea13f6bda5 |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-861c900cf808420d8d5b98ea13f6bda52025-02-03T05:45:26ZengWileyCase Reports in Infectious Diseases2090-66252090-66332015-01-01201510.1155/2015/537627537627Cepacia Syndrome in a Non-Cystic Fibrosis PatientNaomi Hauser0Jose Orsini1Department of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, Brooklyn, NY 11206, USABurkholderia (formerly Pseudomonas) cepacia complex is a known serious threat to patients with cystic fibrosis, in whom it has the potential to cause the fatal combination of necrotizing pneumonia, worsening respiratory failure, and bacteremia, known as Cepacia syndrome. The potential for this pathogen to infect non-cystic fibrosis patients is limited and its epidemiology is poorly understood. Previously reported cases of severe Burkholderia cepacia complex lung infection in immunocompetent hosts include pneumonia, bronchiectasis, pyopneumothorax, and cavitary lesions. We present a case of a 64-year-old man with Streptococcus pneumoniae community-acquired pneumonia whose hospital course was complicated by developing cavitary lung lesions, bacteremia, and acute respiratory distress syndrome. Repeated tracheal aspirate and blood cultures grew Burkholderia cepacia. Our case appears to be the first report of Cepacia syndrome in a patient without cystic fibrosis. This report raises concern regarding the potential severity of pulmonary Burkholderia cepacia complex infection and the need to broaden clinicians’ suspicion for Cepacia syndrome. A framework to help diagnose and treat infected non-cystic fibrosis individuals may be useful.http://dx.doi.org/10.1155/2015/537627 |
| spellingShingle | Naomi Hauser Jose Orsini Cepacia Syndrome in a Non-Cystic Fibrosis Patient Case Reports in Infectious Diseases |
| title | Cepacia Syndrome in a Non-Cystic Fibrosis Patient |
| title_full | Cepacia Syndrome in a Non-Cystic Fibrosis Patient |
| title_fullStr | Cepacia Syndrome in a Non-Cystic Fibrosis Patient |
| title_full_unstemmed | Cepacia Syndrome in a Non-Cystic Fibrosis Patient |
| title_short | Cepacia Syndrome in a Non-Cystic Fibrosis Patient |
| title_sort | cepacia syndrome in a non cystic fibrosis patient |
| url | http://dx.doi.org/10.1155/2015/537627 |
| work_keys_str_mv | AT naomihauser cepaciasyndromeinanoncysticfibrosispatient AT joseorsini cepaciasyndromeinanoncysticfibrosispatient |