Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran
Flavonoids are secondary metabolites providing Ultraviolet-visible (UV) spectroscopy protection and color in almost all terrestrial plants and fruits. They have a fused ring system consisting of an aromatic ring and a benzopyran ring with a phenyl substituent. As their biological activities have an...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/620305 |
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| author | Akbar Esmaeili Zahra Mousavi Maryam Shokrollahi Ali Shafaghat |
| author_facet | Akbar Esmaeili Zahra Mousavi Maryam Shokrollahi Ali Shafaghat |
| author_sort | Akbar Esmaeili |
| collection | DOAJ |
| description | Flavonoids are secondary metabolites providing Ultraviolet-visible (UV) spectroscopy protection and color in almost all terrestrial plants and fruits. They have a fused ring system consisting of an aromatic ring and a benzopyran ring with a phenyl substituent. As their biological activities have an impact on human health, they serve as target molecules in the development of new drugs. The objective of this research was to study the antioxidant activity and chemical analysis of the luteoline from Centaurea behen L. (Compositae family). The aerial parts of powdered and dried C. behen were extracted with methanol (MeOH) in a Soxhlet apparatus over a period of 2 days. The concentrated total extract was extracted with petroleum ether, diethylether, and methanol. From the methanol extract of the aerial parts of C. behen, the flavonoid derivative (luteoline) was identified. The aerial parts’ extract demonstrated effective antioxidant activity measured in terms of half-maximal inhibitory concentration (IC50). The product extract has been isolated by UV, column chromatography (CC), and preparative high-performance liquid chromatography (HPLC). The structures involved were elucidated by 1H and 13C nuclear magnetic resonance (NMR) and heteronuclear multiple-bond correlation (HMBC) spectra. The compound identified had not been reported in previous studies of C. behen L. |
| format | Article |
| id | doaj-art-86182fe3c7ab458da8932710a34a6308 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-86182fe3c7ab458da8932710a34a63082025-02-03T01:23:26ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/620305620305Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in IranAkbar Esmaeili0Zahra Mousavi1Maryam Shokrollahi2Ali Shafaghat3Department of Chemical Engineering, North Tehran Branch, Islamic Azad University, P.O. Box 19585/936, Tehran, IranDepartment of Chemical Engineering, North Tehran Branch, Islamic Azad University, P.O. Box 19585/936, Tehran, IranDepartment of Chemical Engineering, North Tehran Branch, Islamic Azad University, P.O. Box 19585/936, Tehran, IranDepartment of Chemistry, Islamic Azad University, Khalkhal Branch, Khalkhal, IranFlavonoids are secondary metabolites providing Ultraviolet-visible (UV) spectroscopy protection and color in almost all terrestrial plants and fruits. They have a fused ring system consisting of an aromatic ring and a benzopyran ring with a phenyl substituent. As their biological activities have an impact on human health, they serve as target molecules in the development of new drugs. The objective of this research was to study the antioxidant activity and chemical analysis of the luteoline from Centaurea behen L. (Compositae family). The aerial parts of powdered and dried C. behen were extracted with methanol (MeOH) in a Soxhlet apparatus over a period of 2 days. The concentrated total extract was extracted with petroleum ether, diethylether, and methanol. From the methanol extract of the aerial parts of C. behen, the flavonoid derivative (luteoline) was identified. The aerial parts’ extract demonstrated effective antioxidant activity measured in terms of half-maximal inhibitory concentration (IC50). The product extract has been isolated by UV, column chromatography (CC), and preparative high-performance liquid chromatography (HPLC). The structures involved were elucidated by 1H and 13C nuclear magnetic resonance (NMR) and heteronuclear multiple-bond correlation (HMBC) spectra. The compound identified had not been reported in previous studies of C. behen L.http://dx.doi.org/10.1155/2013/620305 |
| spellingShingle | Akbar Esmaeili Zahra Mousavi Maryam Shokrollahi Ali Shafaghat Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran Journal of Chemistry |
| title | Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran |
| title_full | Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran |
| title_fullStr | Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran |
| title_full_unstemmed | Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran |
| title_short | Antioxidant Activity and Isolation of Luteoline from Centaurea behen L. Grown in Iran |
| title_sort | antioxidant activity and isolation of luteoline from centaurea behen l grown in iran |
| url | http://dx.doi.org/10.1155/2013/620305 |
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