Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer

Approximately 60% of pancreatic cancers occur in the pancreatic head and may present as obstructive jaundice due to bile duct invasion. Obstructive jaundice often leads to poor general conditions and acute cholangitis, interfering with surgery and chemotherapy and requiring biliary drainage. The fir...

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Main Authors: Masahiro Itonaga, Masayuki Kitano
Format: Article
Language:English
Published: Korean Society of Gastrointestinal Endoscopy 2025-01-01
Series:Clinical Endoscopy
Subjects:
Online Access:http://www.e-ce.org/upload/pdf/ce-2023-294.pdf
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author Masahiro Itonaga
Masayuki Kitano
author_facet Masahiro Itonaga
Masayuki Kitano
author_sort Masahiro Itonaga
collection DOAJ
description Approximately 60% of pancreatic cancers occur in the pancreatic head and may present as obstructive jaundice due to bile duct invasion. Obstructive jaundice often leads to poor general conditions and acute cholangitis, interfering with surgery and chemotherapy and requiring biliary drainage. The first choice of treatment for biliary drainage is the endoscopic transpapillary approach. In unresectable tumors, self-expandable metal stents (SEMSs) are most commonly used and are classified into uncovered and covered SEMSs. Recently, antireflux metal stents and large- or small-diameter SEMSs have become commercially available, and their usefulness has been reported. Plastic stents are infrequently used in patients with resectable biliary obstruction; however, owing to the recent trend in preoperative chemotherapy, SEMSs are frequently used because of the long time to recurrent biliary obstruction. Endoscopic ultrasound-guided biliary drainage (EUS-BD) is often performed in patients who are not eligible for the transpapillary approach, and favorable outcomes have been reported. Different EUS-BD techniques and specialized stents have been developed and can be safely used in high-volume centers. The indications for EUS-BD are expected to further expand in the future.
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spelling doaj-art-860da2d6956140db98be8ad91b6285b62025-02-03T08:08:03ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432025-01-01581405210.5946/ce.2023.2947894Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancerMasahiro ItonagaMasayuki KitanoApproximately 60% of pancreatic cancers occur in the pancreatic head and may present as obstructive jaundice due to bile duct invasion. Obstructive jaundice often leads to poor general conditions and acute cholangitis, interfering with surgery and chemotherapy and requiring biliary drainage. The first choice of treatment for biliary drainage is the endoscopic transpapillary approach. In unresectable tumors, self-expandable metal stents (SEMSs) are most commonly used and are classified into uncovered and covered SEMSs. Recently, antireflux metal stents and large- or small-diameter SEMSs have become commercially available, and their usefulness has been reported. Plastic stents are infrequently used in patients with resectable biliary obstruction; however, owing to the recent trend in preoperative chemotherapy, SEMSs are frequently used because of the long time to recurrent biliary obstruction. Endoscopic ultrasound-guided biliary drainage (EUS-BD) is often performed in patients who are not eligible for the transpapillary approach, and favorable outcomes have been reported. Different EUS-BD techniques and specialized stents have been developed and can be safely used in high-volume centers. The indications for EUS-BD are expected to further expand in the future.http://www.e-ce.org/upload/pdf/ce-2023-294.pdfendoscopic retrograde cholangiopancreatographyendoscopic ultrasound-guided biliary drainagehepatobiliary diseasespancreatic neoplasms
spellingShingle Masahiro Itonaga
Masayuki Kitano
Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
Clinical Endoscopy
endoscopic retrograde cholangiopancreatography
endoscopic ultrasound-guided biliary drainage
hepatobiliary diseases
pancreatic neoplasms
title Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
title_full Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
title_fullStr Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
title_full_unstemmed Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
title_short Endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
title_sort endoscopic biliary drainage for distal bile duct obstruction due to pancreatic cancer
topic endoscopic retrograde cholangiopancreatography
endoscopic ultrasound-guided biliary drainage
hepatobiliary diseases
pancreatic neoplasms
url http://www.e-ce.org/upload/pdf/ce-2023-294.pdf
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AT masayukikitano endoscopicbiliarydrainagefordistalbileductobstructionduetopancreaticcancer