Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1

Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1

Saved in:

Bibliographic Details
Main Authors:	Simeng Lu, Bao-Long Hou, Ting Wang, Keyu Ma, Anli Huang, Xue Wu, Yan-Ni Liang, Zheng Wang
Format:	Article
Language:	English
Published:	American Chemical Society 2025-01-01
Series:	ACS Omega
Online Access:	https://doi.org/10.1021/acsomega.4c11189
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Role of Mitogen-Activated Protein Kinase Pathways in Multifactorial Adverse Cardiac Remodeling Associated with Metabolic Syndrome
by: Mohamed Asrih, et al.
Published: (2013-01-01)

Tomato mitogen-activated protein kinase: mechanisms of adaptation in response to biotic and abiotic stresses
by: Yumei Shi, et al.
Published: (2025-02-01)

Activation of the JNK/SAPK and P38 Mitogen-Activated Protein Kinase Signaling Pathways Sensitize Tumor Cells to Cisplatin-Induced Apoptosis
by: Abdel Mansouri, et al.
Published: (2001-01-01)

ERK1/2 mitogen‐activated protein kinase dimerization is essential for the regulation of cell motility
by: Dalia de laFuente‐Vivas, et al.
Published: (2025-02-01)

Structure-guided identification of mitogen-activated protein kinase-1 inhibitors towards anticancer therapeutics.
by: Md Nayab Sulaimani, et al.
Published: (2025-01-01)

Role of Mitogen-Activated Protein Kinases in Myocardial Ischemia-Reperfusion Injury during Heart Transplantation
by: Giuseppe Vassalli, et al.
Published: (2012-01-01)

An Introduction to USGS Topo Maps
by: Hartwig Hochmair, et al.
Published: (2021-01-01)

An Introduction to USGS Topo Maps
by: Hartwig Hochmair, et al.
Published: (2021-01-01)

Spatial Measurements on USGS Topo Maps
by: Hartwig Hochmair, et al.
Published: (2021-02-01)

Spatial Measurements on USGS Topo Maps
by: Hartwig Hochmair, et al.
Published: (2021-02-01)

N-topo nilpotency in fuzzy neighborhood rings
by: T. M. G. Ahsanullah, et al.
Published: (2004-01-01)

UMA TOPO-ONTOLOGIA DE HEIDEGGER E BACHELARD*
by: GABRIEL KAFURE DA ROCHA
Published: (2020-01-01)

Pharmacological Inhibition of p38 Mitogen-Activated Protein Kinases Affects KC/CXCL1-Induced Intraluminal Crawling, Transendothelial Migration, and Chemotaxis of Neutrophils In Vivo
by: Najia Xu, et al.
Published: (2013-01-01)

CYP2E1 Sensitizes the Liver to LPS- and TNF α-Induced Toxicity via Elevated Oxidative and Nitrosative Stress and Activation of ASK-1 and JNK Mitogen-Activated Kinases
by: Arthur I. Cederbaum, et al.
Published: (2012-01-01)

Tumor Microenvironment‐Responsive Nanoparticles Enhance IDO1 Blockade Immunotherapy by Remodeling Metabolic Immunosuppression
by: Mengna Wang, et al.
Published: (2025-02-01)

Tryptanthrin exerts anti-breast cancer effects both in vitro and in vivo through modulating the inflammatory tumor microenvironment
by: Zeng Qingfang, et al.
Published: (2021-06-01)

Novel FeII and CoII Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA
by: Yi-ning Zhong, et al.
Published: (2016-01-01)

Abelian group in a topos of sheaves: torsion and essential extensions
by: Kiran R. Bhutani
Published: (1989-01-01)

›Modell‹ und ›Topos‹ in der deutschsprachigen Musiktheorie seit Riemann
by: Hans Aerts
Published: (2007-01-01)

Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma
by: Heike Loeser, et al.
Published: (2020-01-01)

In vitro effects of fluticasone propionate on IL-13 production by mitogen-stimulated lymphocytes
by: Gabriele Di Lorenzo, et al.
Published: (2002-01-01)

Az ontológiai ugráson innen és túl – az idős Lukács egy lehetséges (militáns) olvasata
by: István Szentistványi
Published: (2023-10-01)

Vestígios do topos do panegírico na poesia de Geraldo Carneiro
by: Paulo Roberto Sodré, et al.
Published: (2016-01-01)

Formation of Tumorspheres with Increased Stemness without External Mitogens in a Lung Cancer Model
by: Juan Sebastian Yakisich, et al.
Published: (2016-01-01)

Probiotics Can Boost the Antitumor Immunity of CD8+T Cells in BALB/c Mice and Patients with Colorectal Carcinoma
by: Jie Mao, et al.
Published: (2020-01-01)

Enhanced Antitumor Efficacy and Reduced Toxicity in Colorectal Cancer Using a Novel Multifunctional Rg3- Targeting Nanosystem Encapsulated with Oxaliplatin and Calcium Peroxide
by: Xie Y, et al.
Published: (2025-01-01)

A Solution for Implementing Partnership Contracts on the Blockchain Platform Using the Decentralized Finance (DeFi) and the IDO Method
by: Mohammad Yaghoubi, et al.
Published: (2023-08-01)

TopoQual polishes circular consensus sequencing data and accurately predicts quality scores
by: Minindu Weerakoon, et al.
Published: (2025-01-01)

The Studies of Chlorogenic Acid Antitumor Mechanism by Gene Chip Detection: The Immune Pathway Gene Expression
by: Tian Yi Kang, et al.
Published: (2013-01-01)

Muribaculum intestinale-derived 3-hydroxybutyric acid from Heterophyllin B attenuated pulmonary fibrosis through IDO1-mediated ferroptosis
by: Ce Chen, et al.
Published: (2025-02-01)

Fatty Liver and Insulin Resistance in the Liver-Specific Knockout Mice of Mitogen Inducible Gene-6
by: Byung Kil Park, et al.
Published: (2016-01-01)

Rosavin exerts an antitumor role and inactivates the MAPK/ERK pathway in small-cell lung carcinoma in vitro
by: Liu Rui, et al.
Published: (2023-06-01)

Tolerogenic Splenic IDO+ Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis
by: Jie Yang, et al.
Published: (2014-01-01)

"Snowed Up" : le topos montagnard dans Women in Love de D. H. Lawrence
by: Philippe Birgy
Published: (2008-05-01)

Ginsenosides 20R-Rg3 and Rg5 enriched black ginseng inhibits colorectal cancer tumor growth by activating the Akt/Bax/caspase-3 pathway and modulating gut microbiota in mice
by: Peng Yu, et al.
Published: (2025-01-01)

Purification and Characterization of a Mitogenic Lectin from Cephalosporium, a Pathogenic Fungus Causing Mycotic Keratitis
by: Nagaraja N. Nagre, et al.
Published: (2010-01-01)

Topos „świat na opak” i redukcja do absurdu w kampanii społecznej „It’s Illogical”
by: Jacek Grębowiec
Published: (2024-10-01)

The Reversed Canvas: A Topos of Conflict Between Commercial and Aesthetic Values in Nineteenth-Century Paris and London
by: Richard Read
Published: (2023-11-01)

hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways
by: Yan Yu, et al.
Published: (2025-01-01)

Integration of Metabolomics and Transcriptomics to Reveal the Antitumor Mechanism of <i>Dendrobium officinale</i> Polysaccharide-Based Nanocarriers in Enhancing Photodynamic Immunotherapy in Colorectal Cancer
by: Shengchang Tao, et al.
Published: (2025-01-01)