Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1

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Main Authors: Simeng Lu, Bao-Long Hou, Ting Wang, Keyu Ma, Anli Huang, Xue Wu, Yan-Ni Liang, Zheng Wang
Format: Article
Language:English
Published: American Chemical Society 2025-01-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.4c11189
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author Simeng Lu
Bao-Long Hou
Ting Wang
Keyu Ma
Anli Huang
Xue Wu
Yan-Ni Liang
Zheng Wang
author_facet Simeng Lu
Bao-Long Hou
Ting Wang
Keyu Ma
Anli Huang
Xue Wu
Yan-Ni Liang
Zheng Wang
author_sort Simeng Lu
collection DOAJ
format Article
id doaj-art-860518fb88364a0dac6d01d4baf79ba4
institution Kabale University
issn 2470-1343
language English
publishDate 2025-01-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-860518fb88364a0dac6d01d4baf79ba42025-01-28T09:00:47ZengAmerican Chemical SocietyACS Omega2470-13432025-01-011033206322110.1021/acsomega.4c11189Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1Simeng Lu0Bao-Long Hou1Ting Wang2Keyu Ma3Anli Huang4Xue Wu5Yan-Ni Liang6Zheng Wang7Co-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaCo-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaCo-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaCo-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaCo-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaMedical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaCo-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, ChinaCo-construction Collaborative Innovation Center of Chinese Medicine Resources Industrialization by Shaanxi & Education Ministry, State Key Laboratory of Research & Development of Characteristic Qin Medicine Resources (Cultivation), Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, Chinahttps://doi.org/10.1021/acsomega.4c11189
spellingShingle Simeng Lu
Bao-Long Hou
Ting Wang
Keyu Ma
Anli Huang
Xue Wu
Yan-Ni Liang
Zheng Wang
Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1
ACS Omega
title Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1
title_full Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1
title_fullStr Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1
title_full_unstemmed Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1
title_short Antitumor Effects of Tryptanthrin on Colorectal Cancer by Regulating the Mitogen-Activated Protein Kinase Signaling Pathway and Targeting Topo I and IDO1
title_sort antitumor effects of tryptanthrin on colorectal cancer by regulating the mitogen activated protein kinase signaling pathway and targeting topo i and ido1
url https://doi.org/10.1021/acsomega.4c11189
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