Pharmacological evidence supporting a role for IL-1, IL-2 and serotonin in the inflammation induced by Schistosoma mansoni Soluble Egg Antigen (SEA) in rat paws

Pharmacological evidence supporting a role for IL-1, IL-2 and serotonin in the inflammation induced by Schistosoma mansoni Soluble Egg Antigen (SEA) in rat paws

This study intended to characterize pharmacologically the mediator(s ) released in the inflammation induced by Soluble Egg Antigen (SEA), the main antigen released from eggs of Schistosoma mansoni, in rat hindpaws . A single intraplantar injection of 0.1–100 μg SEA at day zero induced a dose-depende...

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Bibliographic Details
Main Authors: C. M. F. Pacheco, C. A. P. Tavares, P. M. Z. Coelho, O. A. Rocha, J. M. M. Santos, F. R. M. Prado, J. N. Francischi
Format: Article
Language:English
Published: Wiley 1998-01-01
Series:Mediators of Inflammation
Subjects:
Schistosoma mansoni
Soluble Egg Antigen (SEA)
Oedema
Serotonin
IL-1
IL-2
Cytokines.
Online Access:http://dx.doi.org/10.1080/09629359890947
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