Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice

Mitigating effects of Jiawei Chaihu Shugan decoction on necroptosis and inflammation of hippocampal neurons in epileptic mice

Abstract Jiawei Chaihu Shugan decoction (JWCHSGD) is a traditional Chinese medicine well-known for its beneficial effects in treating epilepsy (Xianzheng in ancient Chinese), but the molecular mechanism of its action remains unclear. To investigate the molecular mechanism of JWCHSGD’s prevention of...

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Bibliographic Details
Main Authors: Qin Wang, Baijun Qin, Han Yu, Jiawei Zeng, Jingjing Fan, Qiong Wu, Rong Zeng, Haichun Yu, Xian Zhang, Mingfen Li, Yanying Zhou, Limei Diao
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Subjects:
Jiawei Chaihu Shugan decoction
Epilepsy
Hippocampal neurons
Necroptosis
Inflammation
Signaling pathway
Online Access:https://doi.org/10.1038/s41598-025-89275-8
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