Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review
Abstract Tracheo‐bronchial adenoid cystic carcinoma (TBACC) is a rare disease. Its treatment is mainly surgical. We herein describe the clinical and para‐clinical varieties of TBACC as well as their surgical treatment and prognosis. We conducted a retrospective study of eight patients operated on be...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Respirology Case Reports |
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| Online Access: | https://doi.org/10.1002/rcr2.70062 |
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| author | Kaouther Ben Amara Imen Bouassida Rahma Ayadi Mariem Affes Amina Abdelkbir Mahdi Abdennadher Salma Ben Othmen Ayda Ayadi‐Kaddour Hazem Zribi Adel Marghli |
| author_facet | Kaouther Ben Amara Imen Bouassida Rahma Ayadi Mariem Affes Amina Abdelkbir Mahdi Abdennadher Salma Ben Othmen Ayda Ayadi‐Kaddour Hazem Zribi Adel Marghli |
| author_sort | Kaouther Ben Amara |
| collection | DOAJ |
| description | Abstract Tracheo‐bronchial adenoid cystic carcinoma (TBACC) is a rare disease. Its treatment is mainly surgical. We herein describe the clinical and para‐clinical varieties of TBACC as well as their surgical treatment and prognosis. We conducted a retrospective study of eight patients operated on between 1994 and 2022 and whose definitive pathological examination concluded with primary TBACC. There were three men and five women with an average age of 44 years. The bronchoscopy found a budding formation reducing the tracheal lumen at the cervical (two cases), middle (two case) and distal trachea and carina (four cases). Bronchial anastomosis resection and sleeve pneumonectomy were the most common procedures. Surgical resections R0 were achieved in five patients. Surgery followed by adjuvant radiotherapy was performed in two patients with incomplete surgical resection R1. The overall survival for all patients with primary ACC was 72% at 5 years. TBACC is a rare and low‐to‐moderate grade malignant tumour. The choice of the surgical procedure and the appropriate approach is challenging to obtain a promising prognosis. |
| format | Article |
| id | doaj-art-85eac3dc4a88476ab1bed16c9664d348 |
| institution | Kabale University |
| issn | 2051-3380 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj-art-85eac3dc4a88476ab1bed16c9664d3482025-01-27T09:16:54ZengWileyRespirology Case Reports2051-33802025-01-01131n/an/a10.1002/rcr2.70062Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature reviewKaouther Ben Amara0Imen Bouassida1Rahma Ayadi2Mariem Affes3Amina Abdelkbir4Mahdi Abdennadher5Salma Ben Othmen6Ayda Ayadi‐Kaddour7Hazem Zribi8Adel Marghli9Thoracic Surgery Department Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaThoracic Surgery Department Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaDepartment of Pathology Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaDepartment of Radiology Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaThoracic Surgery Department Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaThoracic Surgery Department Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaCarcinological Surgery Department Salah Azaiez Institute, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaDepartment of Pathology Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaThoracic Surgery Department Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaThoracic Surgery Department Abderrahmen Mami University Hospital‐Ariana, Faculty of Medicine of Tunis, University of Tunis El Manar Ariana TunisiaAbstract Tracheo‐bronchial adenoid cystic carcinoma (TBACC) is a rare disease. Its treatment is mainly surgical. We herein describe the clinical and para‐clinical varieties of TBACC as well as their surgical treatment and prognosis. We conducted a retrospective study of eight patients operated on between 1994 and 2022 and whose definitive pathological examination concluded with primary TBACC. There were three men and five women with an average age of 44 years. The bronchoscopy found a budding formation reducing the tracheal lumen at the cervical (two cases), middle (two case) and distal trachea and carina (four cases). Bronchial anastomosis resection and sleeve pneumonectomy were the most common procedures. Surgical resections R0 were achieved in five patients. Surgery followed by adjuvant radiotherapy was performed in two patients with incomplete surgical resection R1. The overall survival for all patients with primary ACC was 72% at 5 years. TBACC is a rare and low‐to‐moderate grade malignant tumour. The choice of the surgical procedure and the appropriate approach is challenging to obtain a promising prognosis.https://doi.org/10.1002/rcr2.70062adenoid cystic carcinomabronchusresectionsurvival ratetrachea |
| spellingShingle | Kaouther Ben Amara Imen Bouassida Rahma Ayadi Mariem Affes Amina Abdelkbir Mahdi Abdennadher Salma Ben Othmen Ayda Ayadi‐Kaddour Hazem Zribi Adel Marghli Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review Respirology Case Reports adenoid cystic carcinoma bronchus resection survival rate trachea |
| title | Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review |
| title_full | Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review |
| title_fullStr | Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review |
| title_full_unstemmed | Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review |
| title_short | Primary tracheo‐bronchial adenoid cystic carcinoma: A surgical series with literature review |
| title_sort | primary tracheo bronchial adenoid cystic carcinoma a surgical series with literature review |
| topic | adenoid cystic carcinoma bronchus resection survival rate trachea |
| url | https://doi.org/10.1002/rcr2.70062 |
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