Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functi...
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Language: | English |
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Interna Publishing
2024-10-01
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Series: | Acta Medica Indonesiana |
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Online Access: | https://actamedindones.org/index.php/ijim/article/view/2887 |
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author | Prima Almazini |
author_facet | Prima Almazini |
author_sort | Prima Almazini |
collection | DOAJ |
description | Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functional mitral regurgitation is found in approximately one-third of patients with heart failure with a decreased ejection fraction. Echocardiography is the primary work-up for assessing the anatomy and function of the left ventricle, mitral valve, and severity of functional mitral regurgitation. Additionally, for the latter, an integrated qualitative and quantitative assessment is essential to determine the optimal therapeutic strategy. According to the current guidelines, medical therapy remains the main treatment for functional mitral regurgitation. Yet, transcatheter intervention is a safe and effective treatment option in selected patients. While the effect of surgery on improving mortality in patients with functional mitral regurgitation is not established yet, recent guidelines recommend considering surgery for patients who have undergone coronary artery bypass surgery or other cardiac procedures. |
format | Article |
id | doaj-art-857ec4bc5ce14191867b5cfc9373672f |
institution | Kabale University |
issn | 0125-9326 2338-2732 |
language | English |
publishDate | 2024-10-01 |
publisher | Interna Publishing |
record_format | Article |
series | Acta Medica Indonesiana |
spelling | doaj-art-857ec4bc5ce14191867b5cfc9373672f2025-01-27T04:12:07ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322024-10-01564707Current Diagnosis and Therapeutic Approach of Functional Mitral RegurgitationPrima Almazini0Department of Cardiology and Vascular Medicine Universitas Indonesia - Universitas Indonesia Hospital, Depok, IndonesiaFunctional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functional mitral regurgitation is found in approximately one-third of patients with heart failure with a decreased ejection fraction. Echocardiography is the primary work-up for assessing the anatomy and function of the left ventricle, mitral valve, and severity of functional mitral regurgitation. Additionally, for the latter, an integrated qualitative and quantitative assessment is essential to determine the optimal therapeutic strategy. According to the current guidelines, medical therapy remains the main treatment for functional mitral regurgitation. Yet, transcatheter intervention is a safe and effective treatment option in selected patients. While the effect of surgery on improving mortality in patients with functional mitral regurgitation is not established yet, recent guidelines recommend considering surgery for patients who have undergone coronary artery bypass surgery or other cardiac procedures.https://actamedindones.org/index.php/ijim/article/view/2887functional mitral regurgitationdiagnosismanagement |
spellingShingle | Prima Almazini Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation Acta Medica Indonesiana functional mitral regurgitation diagnosis management |
title | Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation |
title_full | Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation |
title_fullStr | Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation |
title_full_unstemmed | Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation |
title_short | Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation |
title_sort | current diagnosis and therapeutic approach of functional mitral regurgitation |
topic | functional mitral regurgitation diagnosis management |
url | https://actamedindones.org/index.php/ijim/article/view/2887 |
work_keys_str_mv | AT primaalmazini currentdiagnosisandtherapeuticapproachoffunctionalmitralregurgitation |