Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation

Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functi...

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Main Author: Prima Almazini
Format: Article
Language:English
Published: Interna Publishing 2024-10-01
Series:Acta Medica Indonesiana
Subjects:
Online Access:https://actamedindones.org/index.php/ijim/article/view/2887
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author Prima Almazini
author_facet Prima Almazini
author_sort Prima Almazini
collection DOAJ
description Functional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functional mitral regurgitation is found in approximately one-third of patients with heart failure with a decreased ejection fraction. Echocardiography is the primary work-up for assessing the anatomy and function of the left ventricle, mitral valve, and severity of functional mitral regurgitation. Additionally, for the latter, an integrated qualitative and quantitative assessment is essential to determine the optimal therapeutic strategy. According to the current guidelines, medical therapy remains the main treatment for functional mitral regurgitation. Yet, transcatheter intervention is a safe and effective treatment option in selected patients. While the effect of surgery on improving mortality in patients with functional mitral regurgitation is not established yet, recent guidelines recommend considering surgery for patients who have undergone coronary artery bypass surgery or other cardiac procedures.
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spelling doaj-art-857ec4bc5ce14191867b5cfc9373672f2025-01-27T04:12:07ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322024-10-01564707Current Diagnosis and Therapeutic Approach of Functional Mitral RegurgitationPrima Almazini0Department of Cardiology and Vascular Medicine Universitas Indonesia - Universitas Indonesia Hospital, Depok, IndonesiaFunctional mitral regurgitation is characterized by normal structures of the mitral valve and chordae tendinea, but the regurgitation occurs due to geometric changes in the left atrium and left ventricle. This condition can contribute to heart failure progression and lead to a poor prognosis. Functional mitral regurgitation is found in approximately one-third of patients with heart failure with a decreased ejection fraction. Echocardiography is the primary work-up for assessing the anatomy and function of the left ventricle, mitral valve, and severity of functional mitral regurgitation. Additionally, for the latter, an integrated qualitative and quantitative assessment is essential to determine the optimal therapeutic strategy. According to the current guidelines, medical therapy remains the main treatment for functional mitral regurgitation. Yet, transcatheter intervention is a safe and effective treatment option in selected patients. While the effect of surgery on improving mortality in patients with functional mitral regurgitation is not established yet, recent guidelines recommend considering surgery for patients who have undergone coronary artery bypass surgery or other cardiac procedures.https://actamedindones.org/index.php/ijim/article/view/2887functional mitral regurgitationdiagnosismanagement
spellingShingle Prima Almazini
Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
Acta Medica Indonesiana
functional mitral regurgitation
diagnosis
management
title Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
title_full Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
title_fullStr Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
title_full_unstemmed Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
title_short Current Diagnosis and Therapeutic Approach of Functional Mitral Regurgitation
title_sort current diagnosis and therapeutic approach of functional mitral regurgitation
topic functional mitral regurgitation
diagnosis
management
url https://actamedindones.org/index.php/ijim/article/view/2887
work_keys_str_mv AT primaalmazini currentdiagnosisandtherapeuticapproachoffunctionalmitralregurgitation