Synthesis and Anticancer Activity of Bis(2-picolyl)amine Derivatives with a Biaryl Moiety as a Photosensitizer

Synthesis and Anticancer Activity of Bis(2-picolyl)amine Derivatives with a Biaryl Moiety as a Photosensitizer

Metal complexes have potential applications in drug discovery due to their unique properties. For example, zinc(II) ions (Zn<sup>II</sup>) exhibit a high affinity for DNA and have been used as active centers in artificial protein/small-molecule metallonucleases. In this study, we designe...

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Bibliographic Details
Main Authors: Yoshimi Ichimaru, Koichi Kato, Koushirou Sogawa, Daichi Egawa, Hideaki Kato, Kazuaki Katakawa, Wanchun Jin, Masaaki Kurihara, Hiromasa Kurosaki
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Chemistry
Subjects:
DNA photocleavage
pancreatic cancer cell
biphenyl
ROS
double-strand breaks
bpa(dpa)
Online Access:https://www.mdpi.com/2624-8549/7/2/41
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