Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation

Ganglioneuromas of the retroperitoneum are rare cases of benign retroperitoneal tumors that arise from autonomic nerve fibers. Typically remaining asymptomatic even after growing very large, retroperitoneal ganglioneuromas are often discovered incidentally. Given the rather nonspecific, well-defined...

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Main Authors: Charles K. Crawford, BS, Mohammad Yasrab, MD, Linda C. Chu, MD, Elliot K. Fishman, MD
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Radiology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S1930043325000615
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author Charles K. Crawford, BS
Mohammad Yasrab, MD
Linda C. Chu, MD
Elliot K. Fishman, MD
author_facet Charles K. Crawford, BS
Mohammad Yasrab, MD
Linda C. Chu, MD
Elliot K. Fishman, MD
author_sort Charles K. Crawford, BS
collection DOAJ
description Ganglioneuromas of the retroperitoneum are rare cases of benign retroperitoneal tumors that arise from autonomic nerve fibers. Typically remaining asymptomatic even after growing very large, retroperitoneal ganglioneuromas are often discovered incidentally. Given the rather nonspecific, well-defined, smooth, or lobulated characteristics similar to most neurogenic tumors, retroperitoneal ganglioneuromas are sometimes difficult to diagnose. Surgical resection is the preferred treatment option intended to limit the chance of recurrence or malignant transformation; however, surgery can be restricted by local extension, such as encasement of blood vessels. In this article, we report the case of a 49-year-old female diagnosed with a retroperitoneal ganglioneuroma presenting as abdominal pain and fullness. We focus on the use of radiological imaging modalities to coordinate with surgical pathology for an optimized diagnosis and treatment plan.
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id doaj-art-8536b4098957450883cedae4312fa89a
institution Kabale University
issn 1930-0433
language English
publishDate 2025-04-01
publisher Elsevier
record_format Article
series Radiology Case Reports
spelling doaj-art-8536b4098957450883cedae4312fa89a2025-02-02T05:27:02ZengElsevierRadiology Case Reports1930-04332025-04-0120421632166Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentationCharles K. Crawford, BS0Mohammad Yasrab, MD1Linda C. Chu, MD2Elliot K. Fishman, MD3Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USACorresponding author.; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USADepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USADepartment of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, USAGanglioneuromas of the retroperitoneum are rare cases of benign retroperitoneal tumors that arise from autonomic nerve fibers. Typically remaining asymptomatic even after growing very large, retroperitoneal ganglioneuromas are often discovered incidentally. Given the rather nonspecific, well-defined, smooth, or lobulated characteristics similar to most neurogenic tumors, retroperitoneal ganglioneuromas are sometimes difficult to diagnose. Surgical resection is the preferred treatment option intended to limit the chance of recurrence or malignant transformation; however, surgery can be restricted by local extension, such as encasement of blood vessels. In this article, we report the case of a 49-year-old female diagnosed with a retroperitoneal ganglioneuroma presenting as abdominal pain and fullness. We focus on the use of radiological imaging modalities to coordinate with surgical pathology for an optimized diagnosis and treatment plan.http://www.sciencedirect.com/science/article/pii/S1930043325000615GanglioneuromaGNComputed tomographyRetroperitonealMRIGanglioneuroblastomas
spellingShingle Charles K. Crawford, BS
Mohammad Yasrab, MD
Linda C. Chu, MD
Elliot K. Fishman, MD
Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation
Radiology Case Reports
Ganglioneuroma
GN
Computed tomography
Retroperitoneal
MRI
Ganglioneuroblastomas
title Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation
title_full Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation
title_fullStr Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation
title_full_unstemmed Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation
title_short Retroperitoneal ganglioneuroma simulating lymphoma: An unusual case presentation
title_sort retroperitoneal ganglioneuroma simulating lymphoma an unusual case presentation
topic Ganglioneuroma
GN
Computed tomography
Retroperitoneal
MRI
Ganglioneuroblastomas
url http://www.sciencedirect.com/science/article/pii/S1930043325000615
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AT mohammadyasrabmd retroperitonealganglioneuromasimulatinglymphomaanunusualcasepresentation
AT lindacchumd retroperitonealganglioneuromasimulatinglymphomaanunusualcasepresentation
AT elliotkfishmanmd retroperitonealganglioneuromasimulatinglymphomaanunusualcasepresentation