Bidirectional lipid droplet velocities are controlled by differential binding strengths of HCV core DII protein.

Host cell lipid droplets (LD) are essential in the hepatitis C virus (HCV) life cycle and are targeted by the viral capsid core protein. Core-coated LDs accumulate in the perinuclear region and facilitate viral particle assembly, but it is unclear how mobility of these LDs is directed by core. Herei...

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Bibliographic Details
Main Authors: Rodney K Lyn, Graham Hope, Allison R Sherratt, John McLauchlan, John Paul Pezacki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0078065
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