Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline

Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. Morbidity and mortality disproportionately affect individuals born between 1945 and 1975. The recent development of well-t...

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Main Authors: Daniel J Smyth, Duncan Webster, Lisa Barrett, Mark MacMillan, Lisa McKnight, Frank Schweiger
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2014/109046
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author Daniel J Smyth
Duncan Webster
Lisa Barrett
Mark MacMillan
Lisa McKnight
Frank Schweiger
author_facet Daniel J Smyth
Duncan Webster
Lisa Barrett
Mark MacMillan
Lisa McKnight
Frank Schweiger
author_sort Daniel J Smyth
collection DOAJ
description Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. Morbidity and mortality disproportionately affect individuals born between 1945 and 1975. The recent development of well-tolerated and highly effective therapies for chronic HCV infection represents a unique opportunity to dramatically reduce rates of HCV-related complications and their costs. Critical to the introduction of such therapies will be well-designed provincial programming to ensure immediate treatment access to individuals at highest risk for complication, and well-defined strategies to address the global treatment needs of traditionally high-risk and marginalized populations. HCV practitioners in New Brunswick created a provincial strategy that stratifies treatment according to those at highest need, measures clinical impact, and creates evaluation strategies to demonstrate the significant direct and indirect cost savings anticipated with curative treatments.
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institution Kabale University
issn 2291-2789
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publishDate 2014-01-01
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series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-85145a9ba75840d9911e595a8493e3792025-02-03T01:00:10ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972014-01-01281052953410.1155/2014/109046Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation GuidelineDaniel J Smyth0Duncan Webster1Lisa Barrett2Mark MacMillan3Lisa McKnight4Frank Schweiger5Horizon Health Network, New Brunswick, CanadaHorizon Health Network, New Brunswick, CanadaCapital Health, Halifax, Nova Scotia, CanadaHorizon Health Network, New Brunswick, CanadaHorizon Health Network, New Brunswick, CanadaHorizon Health Network, New Brunswick, CanadaChronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. Morbidity and mortality disproportionately affect individuals born between 1945 and 1975. The recent development of well-tolerated and highly effective therapies for chronic HCV infection represents a unique opportunity to dramatically reduce rates of HCV-related complications and their costs. Critical to the introduction of such therapies will be well-designed provincial programming to ensure immediate treatment access to individuals at highest risk for complication, and well-defined strategies to address the global treatment needs of traditionally high-risk and marginalized populations. HCV practitioners in New Brunswick created a provincial strategy that stratifies treatment according to those at highest need, measures clinical impact, and creates evaluation strategies to demonstrate the significant direct and indirect cost savings anticipated with curative treatments.http://dx.doi.org/10.1155/2014/109046
spellingShingle Daniel J Smyth
Duncan Webster
Lisa Barrett
Mark MacMillan
Lisa McKnight
Frank Schweiger
Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
Canadian Journal of Gastroenterology and Hepatology
title Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
title_full Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
title_fullStr Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
title_full_unstemmed Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
title_short Transitioning to Highly Effective Therapies for the Treatment of Chronic Hepatitis C Virus Infection: A Policy Statement and Implementation Guideline
title_sort transitioning to highly effective therapies for the treatment of chronic hepatitis c virus infection a policy statement and implementation guideline
url http://dx.doi.org/10.1155/2014/109046
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