A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation

BackgroundEmotion regulation (ER) and distress tolerance (DT) are considered transdiagnostic risk factors for a range of anxiety disorders. This study investigated the relationship between anxiety sensitivity (AS) and health anxiety (HA) in the general population, focusing on the mediating roles of...

Full description

Saved in:
Bibliographic Details
Main Authors: Hamid Mohsenabadi, Mohammadreza Pirmoradi, Komeil Zahedi Tajrishi, Banafsheh Gharraee
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Psychiatry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1478442/full
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832539910227099648
author Hamid Mohsenabadi
Mohammadreza Pirmoradi
Komeil Zahedi Tajrishi
Banafsheh Gharraee
author_facet Hamid Mohsenabadi
Mohammadreza Pirmoradi
Komeil Zahedi Tajrishi
Banafsheh Gharraee
author_sort Hamid Mohsenabadi
collection DOAJ
description BackgroundEmotion regulation (ER) and distress tolerance (DT) are considered transdiagnostic risk factors for a range of anxiety disorders. This study investigated the relationship between anxiety sensitivity (AS) and health anxiety (HA) in the general population, focusing on the mediating roles of DT and ER.MethodsThe study was conducted as a cross-sectional survey from October to December 2023 in Tehran Province, Iran. A total of 971 individuals participated in this study (52.8% female; mean age 39.04 years, SD=10.64). Participants completed self-report questionnaires to assess HA (The Short Health Anxiety Inventory), AS (The Anxiety Sensitivity Index-3), DT (The 15-item Distress Tolerance Scale) and ER (The 10-item Emotion Regulation Questionnaire). We used structural equation modeling (SEM) to examine the hypothesis that DT and ER would mediate the relationship between AS and the HA.ResultsAS was modestly related to all measures (r from -0.40 to 0.55). According to the SEM analysis, AS (β = 0.45, 95%CI [0.34, 0.56]) had a significant direct effect on HA. However, the analysis of the indirect effects revealed that both DT (β = 0.10, 95% CI [0.06, 0.16]) and emotion regulation strategies—cognitive reappraisal (β = 0.06, 95% CI [0.01, 0.11]) and expressive suppression (β = 0.11, 95% CI [0.06, 0.18])—act as partial mediators in the relationship between AS and HA.ConclusionsAS plays a crucial role in predisposing individuals to HA. The mediating roles of DT and ER provide insight into the link between AS and HA. Nevertheless, the study’s cross-sectional design and reliance on a non-clinical sample limit the applicability of the results. Further research involving different samples and intervention studies is needed to validate and expand upon these findings.
format Article
id doaj-art-84e543c458eb4f89a0ada07cca85c487
institution Kabale University
issn 1664-0640
language English
publishDate 2025-02-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Psychiatry
spelling doaj-art-84e543c458eb4f89a0ada07cca85c4872025-02-05T07:31:50ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402025-02-011610.3389/fpsyt.2025.14784421478442A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulationHamid MohsenabadiMohammadreza PirmoradiKomeil Zahedi TajrishiBanafsheh GharraeeBackgroundEmotion regulation (ER) and distress tolerance (DT) are considered transdiagnostic risk factors for a range of anxiety disorders. This study investigated the relationship between anxiety sensitivity (AS) and health anxiety (HA) in the general population, focusing on the mediating roles of DT and ER.MethodsThe study was conducted as a cross-sectional survey from October to December 2023 in Tehran Province, Iran. A total of 971 individuals participated in this study (52.8% female; mean age 39.04 years, SD=10.64). Participants completed self-report questionnaires to assess HA (The Short Health Anxiety Inventory), AS (The Anxiety Sensitivity Index-3), DT (The 15-item Distress Tolerance Scale) and ER (The 10-item Emotion Regulation Questionnaire). We used structural equation modeling (SEM) to examine the hypothesis that DT and ER would mediate the relationship between AS and the HA.ResultsAS was modestly related to all measures (r from -0.40 to 0.55). According to the SEM analysis, AS (β = 0.45, 95%CI [0.34, 0.56]) had a significant direct effect on HA. However, the analysis of the indirect effects revealed that both DT (β = 0.10, 95% CI [0.06, 0.16]) and emotion regulation strategies—cognitive reappraisal (β = 0.06, 95% CI [0.01, 0.11]) and expressive suppression (β = 0.11, 95% CI [0.06, 0.18])—act as partial mediators in the relationship between AS and HA.ConclusionsAS plays a crucial role in predisposing individuals to HA. The mediating roles of DT and ER provide insight into the link between AS and HA. Nevertheless, the study’s cross-sectional design and reliance on a non-clinical sample limit the applicability of the results. Further research involving different samples and intervention studies is needed to validate and expand upon these findings.https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1478442/fullanxiety sensitivityhealth anxietydistress toleranceemotion regulationtransdiagnostic approach
spellingShingle Hamid Mohsenabadi
Mohammadreza Pirmoradi
Komeil Zahedi Tajrishi
Banafsheh Gharraee
A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation
Frontiers in Psychiatry
anxiety sensitivity
health anxiety
distress tolerance
emotion regulation
transdiagnostic approach
title A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation
title_full A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation
title_fullStr A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation
title_full_unstemmed A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation
title_short A transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety: the mediated roles of distress tolerance and emotion regulation
title_sort transdiagnostic approach to investigate of the relationships between anxiety sensitivity and health anxiety the mediated roles of distress tolerance and emotion regulation
topic anxiety sensitivity
health anxiety
distress tolerance
emotion regulation
transdiagnostic approach
url https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1478442/full
work_keys_str_mv AT hamidmohsenabadi atransdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT mohammadrezapirmoradi atransdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT komeilzaheditajrishi atransdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT banafshehgharraee atransdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT hamidmohsenabadi transdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT mohammadrezapirmoradi transdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT komeilzaheditajrishi transdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation
AT banafshehgharraee transdiagnosticapproachtoinvestigateoftherelationshipsbetweenanxietysensitivityandhealthanxietythemediatedrolesofdistresstoleranceandemotionregulation