Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
American Chemical Society
2024-12-01
|
| Series: | ACS Omega |
| Online Access: | https://doi.org/10.1021/acsomega.4c09231 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832541232329392128 |
|---|---|
| author | Renan A. Gomes Marcelo D. Polêto Hugo Verli Vitor M. Almeida Sandro R. Marana Andreas Bender Bruna F. Godoi Vinícius T. L. Rodrigues Flavio da S. Emery Gustavo H. G. Trossini |
| author_facet | Renan A. Gomes Marcelo D. Polêto Hugo Verli Vitor M. Almeida Sandro R. Marana Andreas Bender Bruna F. Godoi Vinícius T. L. Rodrigues Flavio da S. Emery Gustavo H. G. Trossini |
| author_sort | Renan A. Gomes |
| collection | DOAJ |
| format | Article |
| id | doaj-art-84b95d7702714ba4bf29df2b99cf23a8 |
| institution | Kabale University |
| issn | 2470-1343 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | ACS Omega |
| spelling | doaj-art-84b95d7702714ba4bf29df2b99cf23a82025-02-04T09:05:16ZengAmerican Chemical SocietyACS Omega2470-13432024-12-011043808381910.1021/acsomega.4c09231Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma bruceiRenan A. Gomes0Marcelo D. Polêto1Hugo Verli2Vitor M. Almeida3Sandro R. Marana4Andreas Bender5Bruna F. Godoi6Vinícius T. L. Rodrigues7Flavio da S. Emery8Gustavo H. G. Trossini9Departamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, BrazilCentro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, BrazilCentro de Biotecnologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, BrazilDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, BrazilDepartamento de Bioquímica, Instituto de Química, Universidade de São Paulo, São Paulo, BrazilCentre for Molecular Informatics, Department of Chemistry, University of Cambridge, Cambridge, U.K.Centre for Research and Advancement in Fragments and Molecular Targets (CRAFT), Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, BrazilCentre for Research and Advancement in Fragments and Molecular Targets (CRAFT), Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, BrazilCentre for Research and Advancement in Fragments and Molecular Targets (CRAFT), Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, São Paulo, BrazilDepartamento de Farmácia, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazilhttps://doi.org/10.1021/acsomega.4c09231 |
| spellingShingle | Renan A. Gomes Marcelo D. Polêto Hugo Verli Vitor M. Almeida Sandro R. Marana Andreas Bender Bruna F. Godoi Vinícius T. L. Rodrigues Flavio da S. Emery Gustavo H. G. Trossini Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei ACS Omega |
| title | Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei |
| title_full | Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei |
| title_fullStr | Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei |
| title_full_unstemmed | Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei |
| title_short | Fragment Screening Reveals Novel Scaffolds against Sirtuin-2-Related Protein 1 from Trypanosoma brucei |
| title_sort | fragment screening reveals novel scaffolds against sirtuin 2 related protein 1 from trypanosoma brucei |
| url | https://doi.org/10.1021/acsomega.4c09231 |
| work_keys_str_mv | AT renanagomes fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT marcelodpoleto fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT hugoverli fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT vitormalmeida fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT sandrormarana fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT andreasbender fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT brunafgodoi fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT viniciustlrodrigues fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT flaviodasemery fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei AT gustavohgtrossini fragmentscreeningrevealsnovelscaffoldsagainstsirtuin2relatedprotein1fromtrypanosomabrucei |