Aspartame and ischemic stroke: unraveling the molecular link through network toxicology and molecular docking analysis
Abstract Aspartame, a widely used artificial sweetener, remains controversial due to neurotoxic risks from its metabolites—phenylalanine, aspartic acid, and methanol. While epidemiological studies link artificial sweeteners to cerebrovascular disease, the molecular mechanisms connecting aspartame to...
Saved in:
| Main Authors: | Tianyu Zhang, Tao Wang, Kuangyang Yu, Changren huang, Kunyang Bao |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-08898-z |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Aspartame in the Diet: A Contribution to the Debate on Safety and Health Impact
by: Milena Biernikiewicz, et al.
Published: (2025-02-01) -
Aspartame-Induced Headache
by: J Gordon Millichap
Published: (1994-11-01) -
Unraveling DINCH – Induced hepatotoxicity mechanisms via network toxicology and molecular docking with experimental validation
by: Jingxin Xin, et al.
Published: (2025-07-01) -
Network toxicology and molecular docking reveal the potential link between acrylamide exposure and breast cancer
by: Zhaoda Duan, et al.
Published: (2025-07-01) -
Aspartame increases the risk of liver cancer through CASP1 protein: A comprehensive network analysis insights
by: Ni-ren Li, et al.
Published: (2025-04-01)